alzheimer-s

Documents about alzheimer-s

• L-Leucine Upregulates Lysosomal Biogenesis and Autophagy to Lower Plaques in 5XFAD Mouse Model of Alzheimer's Disease.#4275NCBI PubMed Central
• Trajectories of plasma and CSF MTBR-tau243 and phosphorylated-tau species across the Alzheimer's disease continuum#5438Europe PMC
• Substituting blood-based biomarkers for imaging measures in Alzheimer's disease studies: implications for sample size and bias.#8975NCBI PubMed Central
• Long-read sequencing reveals diverse haplotypes and common structural variants in Alzheimer's Disease GWAS loci#13875bioRxiv / medRxiv
• Alzheimer's disease and related dementias and related health conditions among American Indian and Alaska Native Medicare beneficiaries.#122996NCBI PubMed Central
• Evaluation of Precuneus and Fusiform Gyrus-Based Radiomic biomarkers for Alzheimer's disease Classification and Progression#127865bioRxiv / medRxiv
• Endothelial NAD(+) depletion drives vascular senescence and neuroinflammation via mtDNA-cGAS/STING-CD38 signaling in Alzheimer's disease.#135725NCBI PubMed Central
• Dysregulated glucose metabolism in the visual cortex of human subjects with mild cognitive impairment and Alzheimer’s disease.#135884NCBI PubMed Central
• Outreach, Recruitment and Engagement Cores of NIA-designated Alzheimer's Disease Research Centers: Current strategies and future directions.#135998NCBI PubMed Central
• Improved classification of Alzheimer's disease and mild cognitive impairment through dynamic functional network analysis#139160arXiv (OAI)
• Human iPSC-derived GABAergic interneuron transplantation restores circuit balance and cognitive function in an Alzheimer's disease model.#140484NCBI PubMed Central
• Non-Invasive Temporal Interference Electrical Stimulation Modulates Neurotransmitter Release and Improves Aberrant Neural Oscillations in Alzheimer's Disease.#157883NCBI PubMed Central
• A quasi-experimental study comparing a VR, computer-based, and face-to-face Alzheimer's embodiment education scenario, "Beatriz".#160008NCBI PubMed Central
• Feeding the Mind: Dietary Consumption and Neural Aging#169586Scholar Commons
• Sleep complaints and genetic risk of Alzheimer's disease in older women: associations with memory and tau deposition.#170495NCBI PubMed Central
• The association between midlife neighbourhood walkability and Alzheimer's disease in women: a prospective nested case-control study.#174484NCBI PubMed Central
• Small-molecule PCSK9 inhibition enhances BBB amyloid-β clearance and suppresses microglial inflammation in Alzheimer's disease models.#220899NCBI PubMed Central
• Reproducibility-driven discovery and systematic benchmarking reveal a robust cerebrospinal fluid proteomic signature in Alzheimer's disease#230277bioRxiv / medRxiv
• Microbiome functional gene pathways are indicative of cognitive performance in older adults at risk for Alzheimer's disease.#232261NCBI PubMed Central
• The interventional effect of acupuncture on overall cognitive function in Alzheimer's disease spectrum disorders: A meta-analysis.#242169NCBI PubMed Central
• Taliglucerase Alfa Reduces Amyloid-β Burden by Restoring Autophagic Pathways in a Neuronal Model of Alzheimer's Disease.#255153NCBI PubMed Central
• Integrative Transcriptomic, Network, and Machine Learning Analyses Identify Genistein and Resveratrol-Associated Therapeutic Targets in Alzheimer's Disease.#258015NCBI PubMed Central
• Effects of <i>Phoenix dactylifera</i> against Streptozotocin‐Aluminium Chloride Induced Alzheimer’s Rats and Their In Silico Study#262240HAL (France)
• Early microglial response to amyloid plaques drives sleep loss in Alzheimer's disease#273346Europe PMC
• A Partial Least Squares Analysis of the self reference effect in Alzheimer's disease: A reply to Irish#280316HAL (France)
• Contributions of the Alzheimer's Disease Neuroimaging Initiative to advancing AD research: a targeted review of recent publications.#295059NCBI PubMed Central
• A reappraisal of APOE genetic effects on Alzheimer's disease risk in the Japanese population: a meta-analysis.#312388NCBI PubMed Central
• Alzheimer's Protection by PLCγ2 Compacts Plaques, Redistributes Microglia, and Protects Synapses in App(NL) (-G-F) Mice.#319053NCBI PubMed Central
• Advanced diffusion MRI tract signatures in Alzheimer's disease, dementia with Lewy bodies, and the FTD/PPA spectrum.#322870NCBI PubMed Central
• Alzheimer's disease cerebrospinal fluid biomarker levels and APOE genetic status are associated with hippocampal-cerebellar functional connectivity.#327028NCBI PubMed Central
• Fecal miRNome and Proteome Profiling Uncovers Stage-Specific Biomarkers of Alzheimer's Disease in 3×Tg-AD Mice.#342386NCBI PubMed Central
• Tau profiling of brain extracellular vesicles reveals PHF6 peptide as core for pathological tau seeding in Alzheimer's disease#357327HAL (France)
• NavegApp, a serious game for assessing spatial cognition: Diagnostic accuracy in preclinical and prodromal Alzheimer's disease.#360557NCBI PubMed Central
• Prediction of cognitive decline and Alzheimer's disease conversion by a plasma biomarker panel in non-demented individuals.#368266NCBI PubMed Central
• A clinically feasible framework to estimate tau pathology and clinical-biological discordance in the Alzheimer's disease spectrum.#371660NCBI PubMed Central
• Blood Lead Levels and Alzheimer's Disease Mortality in NHANES: Addressing Temporal Confounding Through a Study Exit Covariate#403777bioRxiv / medRxiv
• Theoretical and practical challenges for capturing reserve and resilience in aging and Alzheimer's disease: A narrative review.#404226NCBI PubMed Central
• Deciphering the Multi-Target Therapeutic Mechanisms of Traditional Chinese Medicine Against Alzheimer's Disease: A Network Pharmacology Perspective.#406386NCBI PubMed Central
• Topography of Juxtaventricular white matter hyperintensities and cognitive associations in Alzheimer's disease: a dual-cohort study.#418584NCBI PubMed Central
• Evidence for sexual antagonism and antagonistic pleiotropy in the maintenance of late onset Alzheimer’s disease alleles#424606Europe PMC
• Patient-derived tau-seeded human neuronal chimeras recapitulate mature Alzheimer's tau pathology and uncover human-specific neuronal vulnerability#435620bioRxiv / medRxiv
• Electroencephalography for early Alzheimer's disease diagnosis: from advanced feature engineering to interpretable ai and clinical translation.#437021NCBI PubMed Central
• Tau Protein-Induced Microtubule Degeneration and Quantum Coherence Disruption: Implications for Memory, Consciousness, and Temporal Integration in Alzheimer’s Disease.#437170NCBI PubMed Central
• Aerobic exercise combined with FK866 ameliorates Alzheimer's disease-like pathology in APP/PS1 mice with NAMPT abnormality.#438893NCBI PubMed Central
• The past, the present, and the future of preclinical mouse models for Alzheimer's disease and related dementias.#440633NCBI PubMed Central
• The Impact of Denoising Approaches on the Relationship Between Alzheimer's Disease Diagnostic Status and Network Topology Measures.#440650NCBI PubMed Central
• The Microglial Trem2 R47H Alzheimer's Disease Risk Variant Does Not Detectably Alter Hippocampal Synaptic Transmission in Young Mice#441636bioRxiv / medRxiv
• Sleep disturbances and risk of Alzheimer's disease: a systematic review and meta-analysis of longitudinal cohort studies.#449802NCBI PubMed Central
• Graphomotor performance as a quantitative marker of Alzheimer's disease: a tablet-based case-control ROC study.#469180NCBI PubMed Central
• Sex-specific reproductive and hormonal factors in relation to Alzheimer’s disease-related biomarkers: A Systematic Review#475724Europe PMC