alzheimer-s

Documents about alzheimer-s

• Comorbidities Incorporated to Improve Prediction for Prevalent Mild Cognitive Impairment and Alzheimer's Disease in the HABS-HD Study.#392950NCBI PubMed Central
• Multidomain determinants of perivascular spaces indicate early cerebrovascular vulnerability in individuals at risk of Alzheimer’s disease#398628Europe PMC
• Preventative semaglutide and tirzepatide treatment does not alter disease progression in the 5xFAD mouse model of Alzheimer's disease.#404260NCBI PubMed Central
• Composition and activity of the proteasome in human iPSC-derived neuronal model of early-stage sporadic Alzheimer's disease#405051bioRxiv / medRxiv
• Cerebrovascular Single-Nucleus RNA-Seq Reveals Heat Shock Activation and Vascular Remodeling in Alzheimer's Disease and Primary Tauopathies#405058bioRxiv / medRxiv
• GALM Alleviates Aβ Pathology and Cognitive Deficit Through Increasing ADAM10 Maturation in a Mouse Model of Alzheimer's Disease.#421192NCBI PubMed Central
• Longitudinal 7T MRS Study of Glutamate and GABA Dynamics in Alzheimer’s Disease Progression: From hyper- to hypoexcitation#422490Europe PMC
• MT5-MMP C-terminal mutations reduce C99 and β accumulation: A foundation for peptide-based Alzheimer's interventions#440247bioRxiv / medRxiv
• Unraveling the molecular Nexus of Alzheimer's Disease and HIV encephalitis: The role of cellular senescence and transcriptional regulation.#455191NCBI PubMed Central
• A Novel Nogo-A Receptor Antagonist Peptide Impedes Alzheimer's Disease Pathology by Nogo-A/NgR/ROCK Signaling Pathway.#457564NCBI PubMed Central
• Association between fasting serum uric acid levels and Alzheimer's disease in nursing home residents: a cross-sectional study.#476744NCBI PubMed Central
• From plate to brain: role of mediators and moderators on the impact of diet on Alzheimer's disease.#479408NCBI PubMed Central
• Mitochondrial bioenergetic signatures differentiate asymptomatic from symptomatic Alzheimer’s disease#485178Europe PMC
• Depression-, Anxiety-, and Anger and Cognitive Functions: Findings From a Longitudinal Prospective Study#491917eScholarship
• Evaluating the clinical effects of GLP-1 receptor agonists for Alzheimer's and Parkinson's diseases using minimal clinically important difference: systematic review and meta-analysis.#247461NCBI PubMed Central
• Effects of physical exercise on cognitive impairment in patients with Alzheimer's disease, Parkinson's disease or mild cognitive impairment: a systematic review and meta-analysis.#288888NCBI PubMed Central
• Alzheimer's disease as a systems-level timing disorder: Circadian disruption of glial immunometabolism, brain clearance, and therapeutic responsiveness#5396Europe PMC
• Author Correction: Consuming a modified Mediterranean ketogenic diet reverses the peripheral lipid signature of Alzheimer's disease in humans#5517Europe PMC
• Predicting future cognitive impairment in preclinical Alzheimer's disease using amyloid PET and MRI: a multisite machine learning study#10160bioRxiv / medRxiv
• Wavelet Entropy Analysis of EEG Signals During Wake and Sleep in Patients with Alzheimer’s Disease: A Pilot Study.#67495NCBI PubMed Central
• Exome analysis of 22,319 individuals links extremely rare CNVs and 22q11.21 dosage to Alzheimer's risk#127873bioRxiv / medRxiv
• Genetic correlation analysis of Alzheimer's disease and stroke implicates PHLPP1 as a shared locus in individuals of African ancestry.#140483NCBI PubMed Central
• Sporadic Alzheimer's disease with bipolar-like features: a case report and a brief review of the current research status.#143068NCBI PubMed Central
• Activities of daily living and their neural correlates across the Alzheimer's disease continuum: Evidence from a Latin American cohort.#148144NCBI PubMed Central
• Deletion of TNFR1 in astrocytes restores memory in aged Alzheimer’s disease mice#154136Unpaywall
• Sentiment Analysis of Radiological Narratives and Intracranial MRI Hemorrhage Images for the Prediction of Dementia and Alzheimer's Disease.#154445NCBI PubMed Central
• Glial cytokine modulation improves sleep and circadian disruption in female SAA knock-in mice of Alzheimer's-related pathology.#156931NCBI PubMed Central
• Refining interconnected pathways: Feedback loops and triangulation#188795OSF
• Integrative In Silico and In Vivo Evidence of Quercetin as a Multitarget Neuroprotective Agent in Alzheimer's Disease.#199186NCBI PubMed Central
• Generative AI-assisted Bayesian-frequentist Hybrid Inference in Single-cell RNA Sequencing Analysis for Genes Associated with Alzheimer's Disease#200193bioRxiv / medRxiv
• Transcriptomic Characterization of Regulatory Programs in Lipid-Processing Microglia in Alzheimer's Disease#207035ScholarlyCommons at Penn
• Interactions between blood nutritional biomarkers and apolipoprotein E ε4 in the progression of mild cognitive impairment to alzheimer’s disease#207729The Learning Edge
• Multi-Target Neuroprotective Compound Exhibits EAAT2-Modulating and Alzheimer's Pathology-Attenuating Effects in In Vitro and In Vivo Models.#220859NCBI PubMed Central
• Fabrication of Co-Doped Covalent Organic Framework Nanosheets with Mild Interlayer Stress for Quantitative Detection of Alzheimer's Disease Biomarkers.#232234NCBI PubMed Central
• Modulatory Effect Of Thicapa On The Amyloid Precursor Protein Processing Pathways Of Familial Alzheimer’S Disease Using Fibroblast Cell Lines#237665USM Repository
• Early Detection of Alzheimer's Disease and Related Dementias From Spontaneous Speech Using Foundation Speech and Language Models: Comparative Evaluation.#239609NCBI PubMed Central
• The Alzheimer's disease Burden in China (ABC) study: protocol for a nationwide multicentre cross-sectional and prospective cohort study#241504bioRxiv / medRxiv
• Assessment of medication-related risks for mortality prediction in Alzheimer's disease#254130HAL (France)
• Single-cell atlas reveals the key role of pro-inflammatory IREB2⁺ microglia subsets in the microenvironment of Alzheimer's disease.#262879NCBI PubMed Central
• The Davos Alzheimer's Collaborative Healthcare System Preparedness US Early Detection of Cognitive Impairment Program in primary care: Methodology.#288844NCBI PubMed Central
• Haplotype-resolved DNA methylation at the APOE locus identifies allele-specific epigenetic signatures relevant to Alzheimer’s disease risk.#298873NCBI PubMed Central
• Alzheimer's disease risk prediction from clinical and social determinants of health: a machine learning cohort study in UK Biobank.#308720NCBI PubMed Central
• The Associations of Cerebral Blood Flow and White Matter Hyperintensities with Tau and Amyloid-beta Across the Alzheimer's Disease Spectrum#310942bioRxiv / medRxiv
• In-vitro modelling of Alzheimer's disease using cholinergic neurons derived from human neuroblastoma (SH-SY5Y) retinoic acid-induced differentiation.#312404NCBI PubMed Central
• No evidence of cognitive or psychological impact after returning research Alzheimer disease biomarkers: A delayed-start, noninferiority, randomized clinical trial#321482bioRxiv / medRxiv
• Brain Endothelial Glycocalyx as a Blood-Facing Translational Interface in Alzheimer's Disease: Beyond "Leaky" Barriers Toward Repair-First Stratification.#330718NCBI PubMed Central
• Plasma Biomarkers for Alzheimer's Disease Across the Continuum: A Systematic Review of SIMOA-Based Studies.#342381NCBI PubMed Central
• Osteoimmuno-brain axis: a bridge connecting osteoporosis and cognitive decline and its clinical significance in dementia and Alzheimer's disease.#354523NCBI PubMed Central
• Synchronous nonmonotonic changes in functional connectivity and white matter integrity in a rat model of sporadic Alzheimer's disease#357634Infoscience
• Computer-Aided Drug Design, Synthesis, and In Vitro Safety Evaluation of Carprofen Analogs for Novel Alzheimer's Disease Therapeutics.#375180NCBI PubMed Central