cell-death

Documents about cell-death

• Risk factors and causes of early death in germ cell tumors: a Global Society for Rare GU tumors study#459156Springer Nature OA
• Tislelizumab (Anti-Programmed Cell Death Protein-1 (PD-1) Antibody) in MSI-H or dMMR Solid Tumors#802675ClinicalTrials.gov
• Waterpipe smoke condensate activates autophagy in non-tumorigenic lung epithelial cells: implications for inflammation and stemness#818377Figshare
• A Study of Treatment Patterns and Outcomes in Participants With Stage IIIA Melanoma Receiving Adjuvant Systemic Therapy#841496ClinicalTrials.gov
• Kdm2b, an h3k36-specific demethylase, regulates apoptotic response of gbm cells to trail#954908Koc University Digital Collections
• Combining 2-deoxy-D-glucose with fenofibrate leads to tumor cell death mediated by simultaneous induction of energy and ER stress#934574Koc University Digital Collections
• Exosome Engineering for Blocking Gut Dysbiosis and Inducing Cell Death Mechanisms in Glioblastoma Multiforme#323904Scholar Commons
• Molecular mechanisms of autophagy disorder in diabetic neuropathy: Focusing on signaling pathways and regulation of lipid metabolism#355222PLOS
• <i>CASP1</i> as a key autophagy-related gene in atherosclerosis: Identification by bioinformatics analysis and experimental validation#469502PLOS
• Interplays between nitric oxide and reactive oxygen species in cryptogein signalling#643253HAL (France)
• A Study to Assess Safety of Relatlimab With Ipilimumab in Participants With Advanced Melanoma Who Progressed on Anti-Programmed Cell Death Protein 1 (Anti-PD-1) Treatment#844455ClinicalTrials.gov
• IO102 With Pembrolizumab, With or Without Chemotherapy, as First-line Treatment of Metastatic NSCLC#851540ClinicalTrials.gov
• A Study to Evaluate the Bioavailability of Pembrolizumab (MK-3475) Via Subcutaneous (SC) Injection of Pembrolizumab Formulated With Berahyaluronidase Alfa (MK-5180) [MK-3475A] In Advanced Solid Tumors (MK-3475A-C18)#891620ClinicalTrials.gov
• A Global Phase III Study of Rilvegostomig or Pembrolizumab Plus Chemotherapy for First-Line Treatment of Locally Advanced or Metastatic Squamous Non-small Cell Lung Cancer (NSCLC)#874195ClinicalTrials.gov
• Host-Induced Gene Silencing in Barley Powdery Mildew Reveals a Class of Ribonuclease-Like Effectors#964245ISUDR
• A Study to Evaluate Enfortumab Vedotin (ASG-22CE) in Chinese Participants With Locally Advanced or Metastatic Urothelial Cancer Who Previously Received Platinum-containing Chemotherapy and Programmed Cell Death Protein-1 ( PD 1) / (Programmed Death Ligand-1 (PD-L1) Inhibitor Therapy#841865ClinicalTrials.gov
• Sacituzumab Govitecan With or Without Atezolizumab Immunotherapy in Rare Genitourinary Tumors (SMART) Such as High Grade Neuroendocrine Carcinomas, Adenocarcinoma, and Squamous Cell Bladder/Urinary Tract Cancer, Renal Medullary Carcinoma and Penile C...#851674ClinicalTrials.gov
• Higher susceptibility to Fas ligand induced apoptosis and altered modulation of cell death by tumor necrosis factor-alpha in periarticular tenocytes from patients with knee joint osteoarthritis#405364DataCite
• Caracterização de resposta a estresse oxidativo e mecanismos de morte celular em Boophilus microplus#653128Lume 5.8
• Drawing the line: Clarifying fungal allorecognition from HET domains to het genes to heterokaryon incompatibility#676868HAL (France)
• A Substudy of Investigational Agents in Programmed Cell Death-1/Ligand 1 (PD-1/L1) Refractory Locally Advanced or Metastatic Urothelial Carcinoma (mUC) (MK-3475-04A)#871322ClinicalTrials.gov
• HAIC Plus PD-1 Antibody vs HAIC Plus Sorafenib for Advanced HCC#912416ClinicalTrials.gov
• A Study Of Avelumab In Patients With Locally Advanced Or Metastatic Urothelial Cancer (JAVELIN Bladder 100)#912535ClinicalTrials.gov
• Efficacy and Safety of Pembrolizumab (MK-3475) Plus Enzalutamide Plus Androgen Deprivation Therapy (ADT) Versus Placebo Plus Enzalutamide Plus ADT in Participants With Metastatic Hormone-Sensitive Prostate Cancer (mHSPC) (MK-3475-991/KEYNOTE-991)#883953ClinicalTrials.gov
• A Study of Belzutifan (MK-6482) as Monotherapy and in Combination With Lenvatinib (E7080/MK-7902) With or Without Pembrolizumab (MK-3475) in China Participants With Advanced Renal Cell Carcinoma (MK-6482-010)#993264ClinicalTrials.gov
• 4D-DIA-based proteomics analysis reveals protein changes in expression during palatal development.#350248Figshare
• New mechanistic insight into SARM1 activation: TRIM32-mediated ubiquitination is a key lever that actuates SARM1’s catalytic action, leading to axon degeneration and cell death#653902OKAYAMA UNIVERSITY SCIENTIFIC ACHIEVEMENT REPOSITORY
• Prion propagation is controlled by a hierarchical network involving the nuclear Tfap2c and hnRNP K factors and the cytosolic mTORC1 complex#120228PLOS
• A Study of Pembrolizumab (MK-3475) With or Without Lenvatinib (E7080/MK-7902) as First Line (1L) Intervention in a Programmed Cell Death-ligand 1 (PD-L1) Selected Population With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma (R/M HNSCC) (MK-7902-010/LEAP-010)-China Extension#906694ClinicalTrials.gov
• Immunotherapy by Immune Checkpoint Inhibitors and Nuclear Medicine Imaging: Current and Future Applications#308335HAL (France)
• The VCD legacy: Understanding ovarian cell death mechanisms, elucidating ovarian chemical biotransformation, and developing a physiologically-relevant model of menopause induction#350905Iowa State University Digital Repository
• Programmed Cell Death Ligand 1 PET/CT in Various PD-L1-Related Disease Patients#903232ClinicalTrials.gov
• A Study to Evaluate the Safety, Tolerability, and Antitumor Activity of INCB001158 Plus Epacadostat, With or Without Pembrolizumab, in Advanced Solid Tumors#837331ClinicalTrials.gov
• Efficacy and Descriptive Safety Assessment of Programmed Cell Death Protein-(Ligand) 1 Inhibitors Plus Chemotherapy as First-Line Treatment for Gastric and Gastroesophageal Junction Cancer in Asian and Non-Asian Patients: A Meta-Analysis.#170800NCBI PubMed Central
• TGF beta mediates activation of transglutaminase 2 in response to oxidative stress that leads to protein aggregation#439896S-Space: Seoul National University
• Clinical Relevance of NGS Analysis for High-purity CTC From Cancer Patients With Disruptive Gene Mutation(s)#1047876ClinicalTrials.gov
• Risk Factors for Solid Organ Graft Failure and Death in Hematopoietic Cell Transplant Recipients Undergoing Solid Organ Transplantation: A Retrospective Center for International Blood and Marrow Transplant Research and Organ Procurement and Transplantation Network Study.#305426NCBI PubMed Central
• Nanosecond Electric Pulses as a Novel in Situ Vaccination Strategy for Cancer Treatment: Mechanisms, Challenges and Prospects#1001624ODU Digital Commons
• MK-7684A With or Without Other Anticancer Therapies in Participants With Selected Solid Tumors (MK-7684A-005) (KEYVIBE-005)#844803ClinicalTrials.gov
• Evaluation of the Efficacy and Safety of [18F]-ML-10, as a PET Imaging Radiotracer, in Early Detection of Response of Brain Metastases of Solid Tumors to Radiation Therapy.#889468ClinicalTrials.gov
• Risk Factors for Solid Organ Graft Failure and Death in Solid Organ Transplant Recipients Undergoing Hematopoietic Cell Transplantation: A Retrospective Center for International Blood and Marrow Transplant Research (CIBMTR) and Organ Procurement and Transplantation Network (OPTN) Study.#305427NCBI PubMed Central
• Hesperidin mitigates cognitive and anxiety-like deficits by enhancing hippocampal antioxidant defenses, reducing neuroinflammation, and preventing neuronal apoptosis in a third-trimester-equivalent rat model of developmental ethanol neurotoxicity#311499Europe PMC
• Safety and Preliminary Efficacy of Pumitamig (BNT327), an Investigational Therapy for Patients With Non-small Cell Lung Cancer in Combination With Chemotherapy as First-line or Second-line Treatment#878798ClinicalTrials.gov
• Bypassing the Resistance Mechanisms of the Tumor Ecosystem by Targeting the Endoplasmic Reticulum Stress Pathway Using Ruthenium- and Osmium-Based Organometallic Compounds: An Exciting Long-Term Collaboration with Dr. Michel Pfeffer#344476HAL (France)
• Effect of BM-MSCs on Early Graft Function Recovery After DCD Kidney Transplant.#866207ClinicalTrials.gov
• The Predictive Role of Programmed Death Ligand 1 (PD-L1) and Neutrophil to Lymphocyte Ratio (NLR) in Non-Small Cell Lung Cancer (NSCLC)#417530ClinicalTrials.gov
• Observational Study of Cardiac Arrhythmias During Treatment With BTK Inhibitors or Venetoclax#810967ClinicalTrials.gov
• A Study to Evaluate the Safety, Pharmacokinetics and Pharmacodynamics of ABBV-181 (Budigalimab) in Adult Participants With Human Immunodeficiency Virus (HIV)-1#847283ClinicalTrials.gov
• Correlation of red cell distribution width-to-albumin ratio combined with SOFA score with 28-day all-cause mortality in patients with acute pancreatitis: A retrospective study based on the MIMIC-IV database#631442PLOS
• Probing the correlation of neuronal loss, neurofibrillary tangles, and cell death markers across the Alzheimer's disease Braak stages: a quantitative study in humans#614673eScholarship