clinical-trial

Documents about clinical-trial

• A Clinical Trial to Evaluate the Safety, Tolerability, and Pharmacokinetics of PGDM1400LS Alone and in Combination With VRC07-523LS and PGT121.414.LS in Healthy, HIV-uninfected Adult Participants#158021ClinicalTrials.gov
• A Clinical Trial in Healthy Volunteers and Volunteers With Recurrent Genital Herpes to Study the Safety, Tolerability, and Immune Responses After Vaccination With an Investigational Vaccine Designed to Prevent Genital Herpes Lesions#162566ClinicalTrials.gov
• The use of weighted health-related Quality of Life scores in people with diabetic macular oedema at baseline in a randomized clinical trial#169373Research Repository
• A Long-term Trial to Compare the Effects of Liraglutide and Sulphonylurea (Glimepiride) Both in Combination With Metformin on Clinical, Endothelial and Image Markers of Cardiovascular Risk in Patients With Type 2 Diabetes#217000ClinicalTrials.gov
• Performance of Repeated Measures of (1–3)-β-D-Glucan, Mannan Antigen, and Antimannan Antibodies for the Diagnosis of Invasive Candidiasis in ICU Patients: A Preplanned Ancillary Analysis of the EMPIRICUS Randomized Clinical Trial#226846HAL (France)
• TARGET: A phase I/II open-label multicenter study to assess safety and efficacy of fexagratinib in patients with relapsed/refractory FGFR fusion-positive glioma#235083HAL (France)
• A Pospective, Single-arm, Multicenter Clinical Trial Evaluating Preoperative Neoadjuvant mFOLFOX6 Chemotherapy in Combination With PD1 Monoclonal Antibody in MSS/pMMR Locally Advanced Rectal Cancer#261515ClinicalTrials.gov
• Multicenter, randomized, double-blind clinical trial to evaluate the efficacy and safety of a reduced osmolarity oral rehydration salts solution in children with acute watery diarrhea#277446Repositorio Universidad Peruana Cayetano Heredia
• TaILOR: a randomised trial to compare the clinical and cost-effectiveness of a patient-initiated follow-up (PIFU) strategy compared to standard care pathways in people with inflammatory arthritis: a study protocol.#354886NCBI PubMed Central
• Optimising graft selection in ACL reconstruction (GRASE ACL): a study protocol for a randomised controlled clinical trial investigating quadriceps, hamstring and patella tendon for reconstruction in patients with primary ACL rupture.#457461NCBI PubMed Central
• Clinical Trial to Compare the Immunogenicity, Safety, and Tolerability of an Adjuvanted A(H1N1) Influenza Vaccine Versus Non-Adjuvanted A(H1N1) Influenza Vaccines in Patients With Invasive Solid Tumors#463752ClinicalTrials.gov
• RANDOMISED CONTROLLED TRIAL OF A COMPLEX INTERVENTION TO IMPROVE SCHOOL-BASED HPV VACCINATION FOR ADOLESCENTS: THE HPV. EDU STUDY#471772Figshare
• Efficacy of PD-1 Inhibitor Combination Therapy in Non-small Cell Lung Cancer Patients Who Have Not Achieved Major Pathologic Response After Neoadjuvant Immunotherapy: a Multicenter, Phase II Clinical Trial#28299ClinicalTrials.gov
• Effect of transcutaneous auricular vagus nerve stimulation (taVNS) on postoperative delirium (POD) in elderly patients with non-acute fragile brain function (NFBF): a study protocol of bi-center, double-blind, randomised, controlled clinical trial.#156834NCBI PubMed Central
• A Clinical Trial to Study the Safety, Tolerance and Immunogenic Response to MCV4, Tdap and Bivalent rLP2086 Vaccine When Given at the Same Time to Children Between the Ages of 10 Through 12 Years of Age#217096ClinicalTrials.gov
• Transcatheter and surgical aortic valve replacement for aortic stenosis in France: Trends from 2010 to 2022 and impact of European guidelines and clinical trial results#285430PLOS
• Clinical Trial to Study the COVAC-2 Booster Dose (for COVID-19) in Generally Healthy Adults.#290844ClinicalTrials.gov
• A Phase 1/ 2, First-in-Human, Open-Label, Accelerated-Titration, Two-Part Clinical Trial of TK-8001 in Patients With HLA-A*02:01 Genotype and Advanced-Stage/ Metastatic MAGE-A1+ Solid Tumors#303742ClinicalTrials.gov
• A Clinical Trial Comparing Long-Course Versus Short-Course Radiotherapy Followed by Immunotherapy Combined With Total Neoadjuvant Therapy (TNT) to Long-Course Radiotherapy Followed by TNT in Locally Advanced Rectal Cancer#307455ClinicalTrials.gov
• Phase II Clinical Trial of PD-L1 in Combination With Vinorelbine + Cyclophosphamide + Capecitabine (VEX) Metronomic Chemotherapy With or Without Radiotherapy for Advanced Triple-negative Breast Cancer.#329526ClinicalTrials.gov
• Clinical Trial on Sequential Immunization of Recombinant COVID-19 Vaccine (CHO Cells,NVSI-06-08) and Inactivated COVID-19 Vaccine (Vero Cells) in Population Aged 18 Years and Above#356538ClinicalTrials.gov
• A Double-Blinded, Randomised, Placebo-Controlled Trial of Antibiotic Prophylaxis in Elective Non-Hysterectomy Laparoscopic Surgery for Benign Gynaecological Conditions#398044Australian National Data Services (ANDS)
• Functional near-infrared spectroscopy assessment of the effects of transcranial direct current stimulation combined with transcranial magnetic stimulation on dynamic functional networks in patients with chronic insomnia: randomised, double-blind, parallel-group, controlled clinical trial.#156820NCBI PubMed Central
• Anastrozole Adjuvant Trial - Study of Anastrozole Compared to NOLVADEX (Tamoxifen Citrate) for Adjuvant Treatment of Early Breast Cancer Clinical Studies), Adjunct Cytotoxic Chemotherapy and Malignant Joint Tumor#184845ClinicalTrials.gov
• Protocol for a multisite, parallel-group, randomized clinical trial comparing a brief tele-cognitive behavioral therapy intervention (BRIGHT) with attention control for the reduction of body image-related distress among head and neck cancer survivors.#209622NCBI PubMed Central
• Preoperative low-energy diets for patients with a body mass index >30 kg/m 2 undergoing non-bariatric surgery: pilot feasibility randomized clinical trial and a systematic review and meta-analysis of efficacy data#219312Ora Oxford University Research
• Cannabidiol compared to pharmacological treatment as usual for crack use disorder : a feasibility, preliminary efficacy, parallel, double‑blind, randomized clinical trial#225084Repositório Institucional da UnB
• A Phase I, Multicenter, Clinical Trial to Evaluate the Safety and Immunogenicity of Vaccinia-Derived MN HIV-1 Recombinant Envelope Glycoprotein (rgp160) of Human Immunodeficiency Virus at Two Different Vaccination Schedules#283082ClinicalTrials.gov
• Description of the Tranquillo Phase 3 Clinical Trial Designs/Study Protocols to Assess Ritlecitinib in Adults and Adolescents with Nonsegmental Vitiligo#299150Springer Nature OA
• A Phase I Multicenter Clinical Trial to Evaluate the Safety and Immunogenicity of Vaccinia Derived HIV-1 Recombinant Envelope Glycoprotein (gp160) of Human Immunodeficiency Virus: Evaluation of a 200-mcg Dose#346991ClinicalTrials.gov
• Ipilimumab N01 Plus Sintilimab and Lenvatinib as First-line Therapy for Locally Advanced or Metastatic TFE3-Rearranged Renal Cell Carcinoma: A Prospective, Multicenter, Single-Arm, Phase II Clinical Trial#432896ClinicalTrials.gov
• Pre-exposure prophylaxis with hydroxychloroquine for COVID-19: a double-blind, placebo-controlled randomized clinical trial.#448435Dipòsit Digital de la Universitat de Barcelona
• DLPFC rTMS is more effective than sham or orbitofrontal stimulation for smoking cessation and alters frontal brain activity: A double-blind, sham-controlled randomized clinical trial#5266Europe PMC
• Impact of a Personalized, High-Dose, Intensive Motor Rehabilitation Program, Integrating Advanced Technology for Adults With Central Neurological Conditions (INTeRAcT): Protocol for a Single-Blind Randomized Controlled Trial With a Clinical, Health Economic, and Process Evaluation.#162037NCBI PubMed Central
• Effectiveness of Recovery Colleges: A Nonrandomised Clinical Trial Across Two Years Using Propensity Score Matching: Efficacité des collèges de rétablissement: essai clinique non randomisé sur deux ans utilisant l'appariement par score de propension.#193294NCBI PubMed Central
• Long-term clinical and cost-effectiveness of a fully automated digital cognitive behavioural therapy for insomnia: 2-year follow-up of a single-blind, superiority, randomised controlled trial#210887Europe PMC
• A study protocol for an ongoing multi-arm, randomized, double-blind, sham-controlled clinical trial with digital features, using portable transcranial electrical stimulation and internet-based behavioral therapy for major depression disorders: The PSYLECT study.#255457NCBI PubMed Central
• Body mass index, prebiotic supplementation during pregnancy and gestational diabetes mellitus risk: An effect modification analysis from a randomised controlled trial#299050Research Online
• Validation of the ΔSUV max for Interim PET Interpretation in Diffuse Large B-Cell Lymphoma on the Basis of the GAINED Clinical Trial#304723HAL (France)
• Clinical complete response and predictive factors in HER2-positive early breast cancer treated with neoadjuvant chemotherapy aimed at omission of surgery: an exploratory analysis of the JCOG1806 trial#338806OKAYAMA UNIVERSITY SCIENTIFIC ACHIEVEMENT REPOSITORY
• Inclusion of stabilised rice bran in ready-to-use therapeutic food supports growth in Indonesian children with severe and moderate acute malnutrition: solutions to enhance health with alternative treatments (SEHAT), a double-blinded, randomised clinical trial#347813HAL (France)
• Impact of indispensable amino acid supplementation on gut function in children at high risk of environmental enteropathy: protocol for an international coordinated group of randomised controlled trials#374360HAL (France)
• A Randomized Double-Blind Placebo-Controlled Multicentric Clinical Trial of an Ayurvedic Intervention, Varadi Kwatha Ghana Vati, as an Adjunct vs Treatment as Usual in the Management of Type-2 Diabetes Mellitus: A Study Protocol.#380750NCBI PubMed Central
• A Clinical Trial of Entinostat in Combination With Nivolumab for Patients With Previously Treated Unresectable or Metastatic Cholangiocarcinoma and Pancreatic Adenocarcinoma#407709ClinicalTrials.gov
• The relationship between patient-reported and clinician-assessed outcome measures in Inclusion body myositis - insights from a retrospective cohort study#431730ResearchOnline@ND
• 11β-Hydroxysteroid dehydrogenase type 1 inhibition in idiopathic intracranial hypertension: a double-blind randomized controlled trial#456041Spiral
• OUTSIDE 2: Outdoor swimming as a nature-based intervention, offered in addition to usual care, compared to usual care alone, in people with depression: A study protocol for a randomised controlled trial and economic evaluation#18869bioRxiv / medRxiv
• A Single-center, Phase II Clinical Trial Evaluating the Efficacy of Sacituzumab Tirumotecan in Combination With Tagitanlimab as Neoadjuvant Therapy for PD-L1-positive, Resectable Stage II to IIIB Non-small Cell Lung Cancer (NSCLC)#127587ClinicalTrials.gov
• A Phase I Clinical Trial to Evaluate the Safety and Immunogenicity of 200 Mcg of gp120 (CHO) BIOCINE in MF59 Emulsion Versus the Emulsion Control: Three Injections at 0, 1, and 6 Months#141088ClinicalTrials.gov
• A Phase II, Comparative Study of Seroconversion of Single-Dose and Two-Dose Measles Vaccination in HIV-Infected and HIV-Uninfected Children: A Multicenter Trial of the Pediatric AIDS Clinical Trials Group#143666ClinicalTrials.gov