drug-development

Documents about drug-development

• A biomimetic tubuloid-on-a-chip for human renal fibrosis research and anti-fibrotic drug development.#404394NCBI PubMed Central
• HWS116 Monotherapy in Patients With Advanced Solid Tumors#846629ClinicalTrials.gov
• A Phase 2 Trial to Evaluate the Efficacy and Safety of Linezolid in Tuberculosis Patients. (LIN-CL001)#855486ClinicalTrials.gov
• A Clinical Trial Study to Determine the Effect of an Investigational Drug (SEP-363856) Has on the Way That the Drug Metformin Travels Through the Body in People With Schizophrenia.#892595ClinicalTrials.gov
• STRUCTURAL AND FUNCTIONAL CHARACTERIZATION OF HYPOTHETICAL METHYLTRANSFERASE FROM EIMERIA FOR TARGETED DRUG DEVELOPMENT AGAINST APICOMPLEXAN PARASITES#246116DigitalCommons@Kennesaw State University
• Methodological Development and Assessing Prescribing Determinants Through Cumulative Drug Exposure in Hospitalized Patients: Proof-of-Concept Retrospective Study#68307HAL (France)
• Evaluation of the Protective Efficacy of a Vaccine Derived From the Synthetic CS Protein of Plasmodium Vivax#154720ClinicalTrials.gov
• Organ-on-a-chip as a next-generation tool in drug development: A bibliometric and patent analysis.#312544NCBI PubMed Central
• Development and external validation of a machine learning model for predicting tigecycline-associated drug-induced liver injury.#427718NCBI PubMed Central
• Development of 3D Lung Cancer Model Based on 3D Bioprinting for Drug Screening#673229İzmir Yüksek Teknoloji Enstitüsü
• Intranasal therapies for neonatal hypoxic-ischemic encephalopathy#784431Europe PMC
• From Bench-to-Bedside: A Review of Clinical Trials in Drug Discovery and Development#1000483arXiv (All)
• Methodological Development and Assessing Prescribing Determinants Through Cumulative Drug Exposure in Hospitalized Patients: Proof-of-Concept Retrospective Study.#28228NCBI PubMed Central
• Artificial intelligence and machine learning in smart vaginal formulation development.#193903PubMed
• Improving Vancomycin Therapeutic Drug Monitoring With a Deep Learning-Based Two-Compartment Predictive Model: Development and Validation Study.#255250NCBI PubMed Central
• Development of smart drug delivery systems: Strategies for selective substance release / Maurice Kramer ; Betreuer: Klaus Langer#628905Deutsche Nationalbibliothek
• Therapeutic drug monitoring of zonisamide in children with epilepsy: development and validation of a precise binary prediction model.#685727NCBI PubMed Central
• CBT With Disulfiram and Contingency Management#808044ClinicalTrials.gov
• Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Sutezolid#852496ClinicalTrials.gov
• Development of a Methodology to Design a High Order Sliding Mode Controller for Drug Dosage#864199ClinicalTrials.gov
• An Evaluation of the Development of Nevirapine Induced Mutations in HIV Patients Initiating or Discontinuing Combination Antiretroviral Therapy#867316ClinicalTrials.gov
• Emerging organoids and organoids-on-chip platforms for translational development of antibody‒drug conjugates and next-generation bioconjugates.#1039878NCBI PubMed Central
• Ethical and social recognition of participation in drug clinical trials: French public views on financial compensation for participants#483551PLOS
• Development of a Swiss Surveillance Database for Molecular Epidemiology of Hypervirulent and Multi-drug Resistant Pathogens#123523ClinicalTrials.gov
• First-in-human to proof-of-concept: why experimental medicine studies remain essential in human physiology and drug development.#265374NCBI PubMed Central
• Development of Artemisia absinthium-Enriched β-Glucan Nanoparticle-Based Nanofibers: Physicochemical Characterization and In Vitro Bioactivity#309427OpenMETU
• Regulatory science for AI-based software as a medical device in computational pathology and biomarker-driven drug development.#362189NCBI PubMed Central
• Evaluation of Reproducibility of a Sporozoite Challenge Model for Plasmodium Vivax in Human Volunteers#426637ClinicalTrials.gov
• Intelligent Framework for Adverse Drug Event Identification Using Large Language Models and Retrieval-Augmented Generation: Development and Evaluation Study.#446314NCBI PubMed Central
• A high-throughput screening of circadian modulators using FDA-approved small molecules#637471RUcore, Rutgers University Community Repository
• ChemoINTEL Assay Algorithm Development Study: In-Vitro Cytotoxic Drug Induced Apoptosis Correlation with Patient Clinical Response to Administered Chemotherapy in Patients#844410ClinicalTrials.gov
• A Pharmacokinetic and Drug Interaction Study of JNJ-26489112 in Healthy Volunteers#867094ClinicalTrials.gov
• A Clinical Study of B007 in the Treatment of Primary Membranous Nephropathy.#888224ClinicalTrials.gov
• Induced Pluripotent Stem Cells for the Development of Novel Drug Therapies for Inborn Errors of Metabolism (iPSC-IEM)#900698ClinicalTrials.gov
• Value, development challenges, and strategies for gaining internal endorsement of digitally connected subcutaneous drug delivery devices: a survey of pharmaceutical stakeholders.#1127NCBI PubMed Central
• Alcohol and Drug Facilitated Sexual Violence: Using the World Café Method for a Multi-Stakeholder Collaborative Approach to Prevention Development.#342628NCBI PubMed Central
• Status, challenges, and prospects of artificial intelligence application in gout diagnosis and treatment, drug research and development, and disease monitoring.#430808NCBI PubMed Central
• Retrospective Analysis of Adverse Drug Reactions in Patients with Type 2 Diabetes Mellitus and Development of a Risk Prediction Model.#442875NCBI PubMed Central
• Evaluation of Early Bactericidal Activity in Pulmonary Tuberculosis (TMC207-CL001)#805178ClinicalTrials.gov
• Development and Validation of Learning and Decision-Making Tasks#871876ClinicalTrials.gov
• Evaluation of Early Bactericidal Activity in Pulmonary Tuberculosis (CL-010)#894455ClinicalTrials.gov
• A Phase I Study of HW201877 in Healthy Subjects#902953ClinicalTrials.gov
• Development of a co-produced Theory of Change for optimal health and social care services for women who use drugs or are in treatment for drug use during the perinatal period.#216133STORRE
• A Drug-Drug Interaction Study of Abiraterone Acetate Plus Prednisone With Dextromethorphan and Theophylline in Patients With Metastatic Castration-Resistant Prostate Cancer#1030697ClinicalTrials.gov
• Towards New Business Models for R&D for Novel Antibiotics#169540Scholarly Commons at Boston University School of Law
• Global Responses: The Search for Cures in the Development of Pharmaceuticals#493930Digital Repository @ Maurer Law
• Safety and Efficacy of Study Drug Versus Placebo for Negative Symptoms of Schizophrenia#1031808ClinicalTrials.gov
• Editorial: Advancements in P2X7 antagonists: from mechanistic insights to therapeutic applications#363750DOAJ
• Development and prospective validation of a machine learning model for risk stratification of drug-induced liver injury using real-world clinical data.#406421NCBI PubMed Central
• A clinical decision support system for predicting drug-related adverse effects in pediatric patients with congenital heart disease: Development and retrospective evaluation.#425132NCBI PubMed Central