drug-discovery

Documents about drug-discovery

• Streamlining Drug Discovery with the Aid of Artificial Intelligence and Physics-Based Modeling#220308EliScholar
• Emerging strategies to enhance microbial natural product-based drug discovery.#280892NCBI PubMed Central
• Riboswitch as a drug discovery target – Current status and prospects of its development –#385103J-STAGE (Japan)
• Cyclic Peptides in Modern Drug Discovery: Trends and Therapeutic Directions.#472450NCBI PubMed Central
• Evolving Drug Discovery: Artificial Intelligence and Machine Learning's Impact in Pharmaceutical Research#718792PhilArchive
• Computational Drug Repurposing for All EBS Cases#1010002ClinicalTrials.gov
• A Targeted Redox‐Active Dual‐Action Pt(IV)‐Mn(II) Prodrug Displays Enhanced In Vivo Anticancer Activity#922927HAL (France)
• A Kernel for Open Source Drug Discovery in Tropical Diseases#634595Duke Law Scholarship Repository
• SOAR elucidates biological insights and empowers drug discovery through spatial transcriptomics.#135953NCBI PubMed Central
• Natural Products in Epilepsy Treatment: From Traditional Medicine Towards Computational Drug Discovery.#232396NCBI PubMed Central
• From Virtual Molecules to Clinical Trials: How AI Is Reshaping Preclinical Drug Discovery.#244368NCBI PubMed Central
• Molecular graph Self attention and graph convolution for drug discovery#264944MIT Open Scholarship
• Adjusted imbalance ratio leads to effective AI-based drug discovery against infectious disease#291912HAL (France)
• DrugGen 2: A disease-aware language model for enhancing drug discovery#353074arXiv CS
• The Allosteric Revolution: From Fundamental Biology to Breakthrough Allosteric Drug Discovery.#472437NCBI PubMed Central
• Personalizable Metabolic Models to Enable Immune Characterization and Drug Discovery#683392DigitalCommons@University of Nebraska
• Artificial Intelligence in Drug Design#679445OpenAlex
• Integrating chemical, genetic, and feasibility assessments for anti-tubercular target validation#657790Cornell eCommons
• Uncertainty-aware hybrid deep generative framework for robust and explainable drug discovery.#747NCBI PubMed Central
• Revolutionizing Drug Discovery: The Role of Artificial Intelligence in Accelerating Pharmaceutical Innovation"#105544PhilArchive
• Accelerating Leigh syndrome drug discovery through deep learning screening in brain organoids.#122772NCBI PubMed Central
• Widespread data leakage inflates accuracy and corrupts biomarker discovery in cancer drug response prediction#152642bioRxiv / medRxiv
• <i>Boesenbergia rotunda</i>: From Ethnomedicine to Drug Discovery#163570WIPO
• Deep Learning Methods for Protein–Small Molecule Interactions with Applications to Early-Stage Drug Discovery#216387EliScholar
• Interpreting Omics Data Analysis with Large Language Models for Disease Target and Drug Discovery#298204bioRxiv / medRxiv
• Harnessing Machine Learning for Accelerated Drug Discovery: Opportunities and Unmet Challenges.#319204NCBI PubMed Central
• Graph representation learning: algorithm development and its application to early drug discovery#328220UBIRA ETheses
• A Computational Community Blind Challenge on Pan-Coronavirus Drug Discovery Data.#340643NCBI PubMed Central
• Deep learning for small-molecule drug discovery: From molecular design to clinical translation.#380843NCBI PubMed Central
• Intelligence on the graph: Graph neural networks for mechanistic drug target discovery.#399694NCBI PubMed Central
• Artificial Intelligence in Pharmaceutical Care: Transforming Drug Discovery, Development, and Patient-care Delivery.#421025NCBI PubMed Central
• Applications and prospects of cryo-electron tomography in drug discovery and understanding disease#428249PubMed Central
• Saccharomyces cerevisiae in cancer research: modeling tumor biology and enabling drug discovery.#437001NCBI PubMed Central
• In silico drug discovery pipelines targeting antibiotic resistance: from genomes to leads.#440930NCBI PubMed Central
• Hybrid artificial intelligence and quantum annealing as an optimization layer in drug discovery.#479412NCBI PubMed Central
• Who Certifies the Twin? Institutional Contenders for Trust in the Digital-Twin Economy of Drug Discovery#691491PhilArchive
• Discovering Drug-Like Compounds By Targeting Protein-Protein Interactions Using a Yeast-3-Hybrid System#169623Scholar Commons
• Integrating Human Intestinal Organoids into FDA's New Approach Methodologies for Drug Discovery.#1336NCBI PubMed Central
• Unleashing the power of DNA-encoded libraries for challenging targets in drug discovery.#9689PubMed
• Primary human intestinal organoids model enteric infection of monkeypox virus and enable scalable drug discovery#11605HAL (France)
• Use of a cytochrome P450 humanized mouse model to refine schistosomiasis drug discovery.#15199NCBI PubMed Central
• Ten simple rules for establishing a drug discovery lab in resource-limited settings.#161880NCBI PubMed Central
• ClinASO: An open-source platform for rapid drug discovery of gapmer antisense oligonucleotides.#170710NCBI PubMed Central
• Discovery of drug–omics associations in type 2 diabetes with generative deep-learning models#183842Ora Oxford University Research
• Computational approaches for flavivirus drug discovery: targeting structural and non-structural proteins#234959Europe PMC
• Multi-omics and artificial intelligence for precision drug discovery and potential clinical applications.#258114NCBI PubMed Central
• A new insight into cardiovascular protective potentials of hydroxylated xanthones#302587Universiti Putra Malaysia Institutional Repository
• DiscoVerse: multi-agent pharmaceutical co-scientist for traceable drug discovery and reverse translation.#338460NCBI PubMed Central
• Computer-aided drug discovery: historical foundations, practical AI tools, and emerging ethical considerations.#354744NCBI PubMed Central
• An integrative computational strategy for antidiabetic drug discovery: From QSAR modeling to retrosynthesis.#613363NCBI PubMed Central