human-genetics

Documents about human-genetics

• Amphiregulin-mediated EGFR activation drives both intrinsic and acquired resistance to KRAS G12C inhibitors in KRAS G12C–mutant non-small cell lung cancer#406912Springer Nature OA
• DNA sequencing data for "Stable clonal contribution of lineage-restricted stem cells to human hematopoiesis"#673277api.researchdata.se
• FAK activity sustains intrinsic and acquired ovarian cancer resistance to platinum chemotherapy#491983eScholarship
• CDK1 Inhibition Targets the p53-NOXA-MCL1 Axis, Selectively Kills Embryonic Stem Cells, and Prevents Teratoma Formation#675856eScholarship
• In host evolution of Exophiala dermatitidis in cystic fibrosis lung micro-environment#491844eScholarship
• Genomics discovery of giant fungal viruses from subsurface oceanic crustal fluids#609388eScholarship
• Structure-based discovery of NANOG variant with enhanced properties to promote self-renewal and reprogramming of pluripotent stem cells#683965eScholarship
• Wnt signalling in gynaecological cancers: A future target for personalised medicine?#222221UNSWorks Repository
• Next Steps: Polygenic Indices and Principal Components, 2022-2023: Special Licence Access#263826UK Data Service OAI-PMH Repository (Production)
• Reconstituting development of pancreatic intraepithelial neoplasia from primary human pancreas duct cells#491847eScholarship
• An audit of genetic testing outcomes and sociodemographic factors of patients who received genetic counselling for hereditary breast cancer through the Division of Human Genetics#632366WIReDSpace
• Temporal dynamics of the multi-omic response to endurance exercise training#780565eScholarship
• A lncRNA fine tunes the dynamics of a cell state transition involving Lin28, let-7 and de novo DNA methylation#614709eScholarship
• A genomic catalog of Earth’s microbiomes#491755eScholarship
• Unusual metabolism and hypervariation in the genome of a Gracilibacteria (BD1-5) from an oil degrading community#620165eScholarship
• Mapping autism risk loci using genetic linkage and chromosomal rearrangements#675904eScholarship
• Reprogramming human T cell function and specificity with non-viral genome targeting#814708eScholarship
• Safety and Efficacy Study of TVGV-1 Vaccine to Treat HPV Induced Cervical HSIL#863657ClinicalTrials.gov
• The changing landscape of Fabry disease: Impact of the inclusion of the GLA-gene in broader NGS or WES based panels on the phenotypic spectrum#976632PLOS
• Common alleles at 6q25.1 and 1p11.2 are associated with breast cancer risk for BRCA1 and BRCA2 mutation carriers#179022Lund University Publications
• 1970 British Cohort Study: Polygenic Indices and Principal Components, 2016-2018: Special Licence Access#263827UK Data Service OAI-PMH Repository (Production)
• The Somatic Genomic Landscape of Glioblastoma#983599eScholarship
• Human cathelicidin peptide LL-37 compacts nucleic acids and alters neutrophil extracellular trap structure#996216eScholarship
• SynthCraft: An AI partner for synthetic data generation to support data access and augmentation in healthcare.#167733Apollo
• A multi-modal data resource for investigating topographic heterogeneity in patient-derived xenograft tumors#491767eScholarship
• Assembly and activation of the Hippo signalome by FAT1 tumor suppressor#491786eScholarship
• A framework for integrating genomics, microbial traits, and ecosystem biogeochemistry#634740eScholarship
• FGFR1 and NTRK3 actionable alterations in “Wild-Type” gastrointestinal stromal tumors#784333eScholarship
• A transcriptome-wide association study of 229,000 women identifies new candidate susceptibility genes for breast cancer#983602eScholarship
• Divergent roles for KLF4 and TFCP2L1 in naive ground state pluripotency and human primordial germ cell development#629258eScholarship
• Next Generation-Targeted Amplicon Sequencing (NG-TAS): An optimised protocol and computational pipeline for cost-effective profiling of circulating tumour DNA#226052Apollo
• Scalable Open Science Approach for Mutation Calling of Tumor Exomes Using Multiple Genomic Pipelines#620112eScholarship
• Cross-family and phage-specific gene requirements for Klebsiella infection revealed by scalable RB-TnSeq genetic screens.#624393eScholarship
• Cerebral Cortical Structural Variation and General Cognitive Ability: Evidence From Mendelian Randomization#675914eScholarship
• Millennium Cohort Study: Polygenic Indices and Principal Components, 2015: Special Licence Access#263825UK Data Service OAI-PMH Repository (Production)
• C-terminal domains of histone demethylase JMJ14 interact with a pair of NAC transcription factors to mediate specific chromatin association#491776eScholarship
• BiG-SCAPE 2.0 and BiG-SLiCE 2.0: scalable, accurate and interactive sequence clustering of metabolic gene clusters#612254eScholarship
• Identification of a conserved subset of cold tumors responsive to immune checkpoint blockade#612268eScholarship
• Effects of Drought Stress on the Panicum hallii Microbiome over a Growth Cycle#970651eScholarship
• National Child Development Study: Polygenic Indices and Principal Components, 2002-2004: Special Licence Access#263828UK Data Service OAI-PMH Repository (Production)
• Comprehensive Characterization of Cancer Driver Genes and Mutations#491952eScholarship
• Predictions of rhizosphere microbiome dynamics with a genome-informed and trait-based energy budget model#675991eScholarship
• Polymer-stabilized Cas9 nanoparticles and modified repair templates increase genome editing efficiency#784304eScholarship
• An Integrated Map of Cell Type–Specific Gene Expression in Pancreatic Islets#922163eScholarship
• Unusual Metabolism and Hypervariation in the Genome of a Gracilibacterium (BD1-5) from an Oil-Degrading Community#620050eScholarship
• Adult height is associated with increased risk of ovarian cancer: a Mendelian randomisation study#642253eScholarship
• Large-Scale Evaluation of Common Variation in Regulatory T Cell–Related Genes and Ovarian Cancer Outcome#675878eScholarship
• Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function#780444eScholarship
• Improved genome editing by an engineered CRISPR-Cas12a#983366eScholarship
• Determining the origin of synchronous multifocal bladder cancer by exome sequencing#934567Koc University Digital Collections