bioRxiv / medRxiv
open access
CC BY-NC-ND 4.0
Pretraining Enhances Megabase-Scale Gene Expression Prediction with GeneUnet
Predicting gene expression from DNA sequence across diverse genomic tracks is essential for understanding gene regulation and interpreting non-coding variants. Existing supervised methods are limited to few species and fail to exploit conserved regulatory mechanisms, while DNA foundation models capt
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