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Uncovering hidden enhancers through unbiased in vivo testing

Mannion, Brandon J et al.
eScholarship · Papers
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31-biological-sciences-for-2020
Chromatin signatures are widely used to identify tissue-specific in vivo enhancers, but their sensitivity and specificity remains unclear. Here we show that many developmental enhancers remain undetectable using currently available chromatin data. In an initial comparison of over 1200 developmental
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