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A sibling study of variation in parental mutation rates

Getseva, V. et al.
bioRxiv / medRxiv · Papers · License: CC BY-ND 4.0
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genomics
People are born with variable numbers of de novo germline mutations (DNMs), depending primarily on the ages of their parents. To explore additional causes, we developed an approach to call DNMs from nucleotide differences between siblings in genomic regions inherited identical by descent from both p
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