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From DNA Design to DNA Slimming: Auditable Agentic Discovery of a Deletion-Only Designer

Shor, Joel
arXiv (All) · Papers
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genomicsmachine-learningneural-and-evolutionary-computing
Compact regulatory DNA can free up space in vector payloads, reduce synthesis and assay burden, and expose which sequence features drive predicted activity. Yet most model-based nucleic-acid designers optimize fixed-length sequences through substitutions; they do not ask which bases of an existing f
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