bioRxiv / medRxiv
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Histone H3K9 methylation and Heterochromatin Protein 1 do not limit DNA accessibility in living S. pombe cells
Chromatin is intrinsically repressive, limiting access to DNA, implying a major regulatory role. Studies with nuclei support this model. However, we have shown previously that genomic DNA is completely accessible in living budding yeast and human cells, except for centromeric chromatin. The fission
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