HAL (France)
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Études structurales et fonctionnelles des machineries moléculaires de la voie NHEJ de réparation des cassures double-brin : vers la caractérisation de nouveaux traitements anti-Cancer
Conventional cancer therapies, notably radiotherapy and chemotherapy, aim to generate DNA double-strand breaks (DSBs) to overwhelm DSBs repair pathways in cancer cells and induce their apoptosis. However, certain cancer cells overexpress factors involved in DSB repair pathways, allowing them to cont
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