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Sub-consensus haploid variant calling in long-read sequencing technology

Xavier Zair et al.
PLOS · Papers · License: CC BY 4.0
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genomicsnext-generation-sequencing
Background: Next-generation sequencing (NGS) is vital for tracking viral evolution during outbreaks. Oxford Nanopore Technologies (ONT) offers long-read, cost-effective sequencing, but accurate sub-consensus variant detection remains challenging. LoFreq, a widely used caller for sub-consensus varian
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