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Novel type 1 diabetes polygenic scores improve identification of type 1 diabetes in diverse populations

Nam, S. et al.
bioRxiv / medRxiv · Papers · License: CC BY-NC 4.0
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endocrinology
Most polygenic scores (PS) for type 1 diabetes were developed using European (EUR) ancestry datasets, limiting performance in non-European (non-EUR) populations. We evaluated novel type 1 diabetes PS across diverse populations to assess whether newer models improve prediction in underrepresented pop
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