HAL (France)
open access
Mutations in VP1 and 3A proteins improve binding and replication of rhinovirus C15 in HeLa-E8 cells
Viruses in the rhinovirus C species (RV-C) can cause severe respiratory illnesses in children including pneumonia and asthma exacerbations. A transduced cell line (HeLa-E8) stably expressing the CDHR3-Y(529) receptor variant, supports propagation of RV-C after infection. C15 clinical or recombinant
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