HAL (France)
open access
OMIP‐048 MC: Quantification of calcium sensors and channels expression in lymphocyte subsets by mass cytometry
Calcium (Ca2+ ) signaling controls T-cell activation and functions. Ca2+ concentrations are locally detected and controlled by Ca2+ -sensors (STIM1 and 2 detecting the depletion from ER stores channels) and Ca2+ -channels (ORAI1-3 in the cell membrane and VDAC1 in the outer mitochondrial membrane).
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