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Crowder-specific modulation of hepatitis C virus NS3/4A protease activity and local structural dynamics
Data: RP-HPLC chromatogram of synthesized FRET-substrate; EDANS fluorescence calibration in dilute conditions (no crowder) and in the presence of PEG 2000, PEG 4000, Ficoll 70, Dextran 70, and lysozyme; FRET-substrate fluorescence in the absence and presence of 500 nM EDANS; fluorescence kinetics
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