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Virtual Reality for Pain and Anxiety During HyFoSy

HaEmek Medical Center, Israel · 2026
ClinicalTrials.gov · Datasets · License: Public Domain · 2026
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heart-rate-variabilityinfertilitynavirtual-reality
This randomized controlled study will evaluate whether virtual reality (VR) reduces procedural pain and anxiety in women undergoing hysterosalpingo-foam sonography (HyFoSy), a minimally invasive ultrasound-based procedure used to assess uterine anatomy and fallopian tube patency. Participants will be randomly assigned to either a VR intervention group or a standard-care control group. The primary outcome will be maximum pain experienced during the procedure, assessed using a Visual Analog Scale (VAS). Secondary outcomes will include state anxiety, heart rate variability (as a physiological measure of autonomic response to procedural stress) and patient satisfaction
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