bioRxiv / medRxiv
open access
Action of cofilin on ADP-Pi-containing actin filaments
In cells, the disassembly of actin filaments is tightly controlled by molecular mechanisms where cofilin plays a central role. Cofilin binds to actin filaments cooperatively, forming clusters that lead to the severing of the filaments. Since cofilin binds preferentially filaments that have hydrolyse
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