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The formation of cortical actin arrays in human trabecular meshwork cells in response to cytoskeletal disruption

Murphy, Kaitlin C et al.
eScholarship · Papers
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The cytoskeleton of human trabecular meshwork (HTM) cells is known to be altered in glaucoma and has been hypothesized to reduce outflow facility through contracting the HTM tissue. Latrunculin B (Lat-B) and Rho-associated protein kinase (ROCK) inhibitors disrupt the actin cytoskeleton and are in cl
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