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CloneOT: predicting clone-specific perturbation responses with lineage-supervised neural inverse optimal transport

Chen, Yanshuo et al.
arXiv (All) · Papers
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genomicsmachine-learning
Predicting single-cell perturbation responses requires mapping between two unpaired populations of cells measured before and after the perturbation. Optimal transport (OT) provides a principled framework for constructing such mappings by minimizing the transport cost, and neural OT methods (\textit{
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