Dipòsit Digital de la Universitat de Barcelona
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Structural insights into a conserved mechanism of choline translocation through CHT
Choline is an essential nutrient critical for cellular homeostasis across all domains of life. In humans, choline uptake in cholinergic neurons for its recycling into acetylcholine is mediated by the high-affinity Na+-dependent transporter SLC5A7 (CHT1). Prokaryotes also depend on choline as an osmo
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