bioRxiv / medRxiv
open access
Gene conversion is a key driver of diversity hotspots in M. tuberculosis antigens and virulence-associated loci
Despite the long-held view of Mycobacterium tuberculosis (Mtb) as a genetically conserved pathogen, many genomic regions remain poorly resolved due to high sequence homology and repetitive content. Using complete genome assemblies generated from long-read sequencing of 151 globally representative cl
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