arXiv (All)
open access
Tau creates spatially moving hotspots of amyloid-$β$ secondary nucleation: a reaction-diffusion model
Tau-amyloid-$β$ cross-seeding creates a spatial paradox. Bioavailable tau can promote A$β$42 nucleation, thereby increasing local fibril number and catalytic-site burden; yet the same fibrils consume the free A$β$ monomer required for homotypic secondary nucleation. The region containing the most ta
Conceptio Open Archive
Analyze & explore related research in Conceptio
Connect this record directly into your research workflow or AI agent. Explore citations across open repositories, query full text, and export structured proof bundles.
This document is indexed with metadata only: full text is not available in the archive for this record. Open the official source ↗
Related documents
- Shorter but not more catalytic: an active-site-resolved model of how tau reshapes amyloid-$β$ secondary nucleation#1423323
- Hereditary amyloidosis: Insights into a fibrinogen A variant protein#1358941
- A distinct tau oligomer strain defines the molecular and proteomic landscape of rapidly progressive Alzheimer’s disease#398839
- Connectome-Based Modeling of Mutation-Specific Amyloid-$β$ Aggregation in Familial Alzheimer's Disease#1233622
- Direct interaction between TDP-43 and Tau promotes their co-condensation, while suppressing Tau fibril formation and seeding#461583
Record · ID 1456804
Retrieved via Conceptio: every document is proof-bundled with source, license, and retrieval metadata.
Retrieved via Conceptio: every document is proof-bundled with source, license, and retrieval metadata.
Bring this data into your agent: Connect via MCP or API · 20 free credits to start · no card required
Read the Docs → · View CLI source on GitHub · Conceptio Open Knowledge Archive
Read the Docs → · View CLI source on GitHub · Conceptio Open Knowledge Archive