Skip to main Communities My dashboard Log in Sign up Published April 15, 2026 | Version v1 Journal article Open HOD And Professor ,Department Of Rognidan Evum Vikriti Vigyana ,Indian Institute Of Ayurved, Research And Hospital Rajkot Authors/Creators Kulloli, Krishma (Contact person) Kulloli, Vivekanand (Researcher) Description Background: The gut–brain axis is a bidirectional communication system linking gastrointestinal physiology with emotional and cognitive centers. Disturbances in this axis contribute to altered appetite regulation, emotional eating, and metabolic disorders. Ayurveda conceptualizes this relationship through Agni (digestive fire), Ama (metabolic toxins) , and Manasika Bhava (psychological factors) , where impaired Agni leads to Ama accumulation and Medodhatu vriddhi , ultimately manifesting as Sthoulya (overweight/obesity) . Objective: To evaluate the efficacy of Ayurvedic detox drinks in promoting weight loss by modulating the gut–brain axis and restoring Agni. Methods: A single-case clinical study was conducted on a 38-year-old female (BMI 28.1 kg/m²) presenting with Adhmana (bloating), Alasya (lethargy), impaired concentration, restlessness, and emotional eating behavior. A 30-day intervention protocol comprising seven Ayurvedic detox drinks—Jeera water, Ajwain water, Saunf water, Methi infusion, Triphala decoction, Lemon–Honey Ushnodaka, and Jeera–Ajwain–Saunf combination water—was administered alongside dietary regulation (Laghu Ahara) and lifestyle modifications including pranayama and mindful eating. Results: After 30 days, the patient showed a reduction of 3.8 kg body weight, improvement in digestive function, normalization of bowel habits, reduced bloating, enhanced satiety, and significant decline in emotional eating episodes. Psychological parameters such as restlessness and lack of concentration also improved, indicating better mind–gut coordination. Conclusion : Ayurvedic detox drinks effectively restored Agni, facilitated Ama Pachana , and contributed to regulation of the gut–brain axis , resulting in sustainable weight loss and improved psychological well-being. This integrative approach highlights the relevance of Ayurveda in managing metabolic disorders through holistic gut–mind modulation. Keywords : Gut–brain axis, Agni, Ama, Sthoulya, detox drinks, emotional eating, Ayurveda, Ushnodaka, Medodhatu, gut–mind modulation. Files Files (531.7 kB) Name Size Download all 18.A Single Case Study on Ayurvedic Detox Drinks for Weight Loss via Gut–Brain Axis Regulation.docx md5:f98aaeb8b092a56a4ea1d63a94f74e6a 531.7 kB Download 16 Views 5 Downloads Show more details All versions This version Views Total views 16 16 Downloads Total downloads 5 5 Data volume Total data volume 2.7 MB 2.7 MB More info on how stats are collected.... Versions External resources Indexed in OpenAIRE Communities Details DOI DOI Badge DOI 10.5281/zenodo.19597869 Markdown [](https://doi.org/10.5281/zenodo.19597869) reStructuredText .. image:: https://zenodo.org/badge/DOI/10.5281/zenodo.19597869.svg :target: https://doi.org/10.5281/zenodo.19597869 HTML <a href="https://doi.org/10.5281/zenodo.19597869"><img src="https://zenodo.org/badge/DOI/10.5281/zenodo.19597869.svg" alt="DOI"></a> Image URL https://zenodo.org/badge/DOI/10.5281/zenodo.19597869.svg Target URL https://doi.org/10.5281/zenodo.19597869 Resource type Journal article Publisher Zenodo Published in International Journal of Diagnostics And Research, 3(3), 130-141, ISSN: 2584-2757, 2026. Rights License Creative Commons Attribution 4.0 International The Creative Commons Attribution license allows re-distribution and re-use of a licensed work on the condition that the creator is appropriately credited. Read more Citation Export Technical metadata Created April 15, 2026 Modified April 15, 2026 Jump up About About Policies Infrastructure Principles Projects Roadmap Contact Blog Blog Support Help FAQ Developers REST API OAI-PMH Contribute GitHub Donate Funded by Powered by CERN Data Centre & InvenioRDM Status Privacy policy Cookie policy Terms of Use This site uses cookies. Find out more on how we use cookies Accept all cookies Accept only essential cookies