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From Test Performance to Risk-Based Effect Sizes: A Unified Wald-Type Framework to Design Clinical Validation Studies for Binary and Survival Outcomes
Clinical validation studies of predictive tests are usually designed to focus on sensitivity ($Se$) and specificity ($Sp$), while statistical power is often calculated on regression-effect scales (e.g., risk ratio, hazard ratio). However, these quantities are statistically connected. Here, we provid
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