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Effect of Meat and Egg on TMAO in Plasma and Urine in Subjects with and Metabolic Subjects

Linnaeus University · 2020
ClinicalTrials.gov · Datasets · License: Public Domain · 2020
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gut-microbiotametabolic-syndromemetabolic-syndrome-xnaplasmaurine
The purpose of this clinical trial is to investigate in subjects with and without metabolic syndrome how meals of choline- and carnitine-rich foods (eggs and meat) affect the trimethylamine-N-oxide (TMAO) concentration in blood and urine in relation to the gut microbiota composition. In response to the subjects´ gut microbiota, the concentrations of TMAO in the plasma and urine of subjects with and without metabolic syndrome (MetS) after ingesting choline- and carnitine-rich foods will be compared. On two occasions, participants will receive after overnight fasting meatballs (170 g) or three hard-boiled eggs. Blood will be collected before ingestion and over 6 hours after test food consumption.
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