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Expression of Toll-Like Receptors 2 and 4 in Asthmatic Patients.

Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau · 2009
ClinicalTrials.gov · Datasets · License: Public Domain · 2009
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asthmainnate-immunityna
Introduction: Recently it has involved the role of TLR (toll-like receptors) in the pathogenesis of asthma. TLRs are a family of proteins responsible for the recognition of Pathogen-Associated Molecular Patters (PAMPs). The possible role that TLRs play in IgE-dependent asthma (not eosinophilic) and its recognition as a new endotype asthma, could open new therapeutic expectations. Objective: To analyze the expression of TLR 2 and 4 in monocytes/ macrophages and neutrophils in peripheral blood and induced sputum from asthmatic patients
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