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Tinostamustine Conditioning and Autologous Stem Cell

Mundipharma-EDO GmbH · 2018
ClinicalTrials.gov · Datasets · License: Public Domain · 2018
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Phase 1 The primary objectives of Phase 1 of this study are to: * Establish the safety, toxicity, and maximum tolerated dose (MTD) of the tinostamustine conditioning regimen. * Identify the recommended Phase 2 dose (RP2D) of tinostamustine for use in the Phase 2 portion of the study. The secondary objective of Phase 1 of this study is to: \- Investigate the pharmacokinetics (PK) of tinostamustine.
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