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A Phase III Study to Evaluate the Efficacy and Safety of ZM-H1505R in Patients With CHB

Shanghai Zhimeng Biopharma, Inc. · 2025
ClinicalTrials.gov · Datasets · License: Public Domain · 2025
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chronic-hepatitis-bhepatitis-b
This study is divided into two parts. Part A is a multicenter, randomized, double-blind, placebo controlled phase Ill clinical trial, designed to evaluate the efficacy and safety of ZM-H1505R in combination with NAs versus NAs monotherapy with HBV DNA ≥ 50 IU/mL and are HBeAg positive who have received NAs monotherapy for at least 12months.Part B is an open-label extension and follow-up period designed to evaluate the long-term safety and efficacy of ZM-H1505R in combination with NAs.
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