crispr-cas9

Documents about crispr-cas9

• In-Depth Characterization of Stem Cell Potency and Genotoxicity for Clinical-Scale Ex Vivo CRISPR/Cas9 Gene Editing#294242Europe PMC
• Enhanced Rice Yellow Mottle Virus Resistance via CRISPR/Cas9-Targeted Mutagenesis of the Rice eIF(iso)4G Gene.#378602NCBI PubMed Central
• CRISPR/Cas9-mediated mutagenesis of BnaAOG1s reveals functional divergence in silique and seed development in Brassica napus L.#427819NCBI PubMed Central
• PNPLA3 I148M drives ferroptosis due to decline of NAD+, predisposing to fatty liver disease#634963eScholarship
• Unravelling the molecular biology of cheese ripening fungus, Penicillium camemberti#655316University of Nottingham Repository
• Supplementary Information of "Robust genome editing in multiple dicot crops via a Cas9-TREX2 fusion with intron-mediated polycistronic tRNA-sgRNA system"#226645Figshare
• OmniEdit: A unified CRISPR/Cas9 platform for precise genome engineering and strain optimization of the Cordyceps militaris cell factory.#222978NCBI PubMed Central
• CRISPR-Cas9 Induced Knockout of BEL5 in Tetraploid Potato: Optimized Methodology via Repeated de novo Regeneration and Impact on Tuberization#471361bioRxiv / medRxiv
• Interfering with DNA repair pathways to enhance CRISPR-Cas9-mediated homology-directed repair in a chelicerate genetic model.#823606NCBI PubMed Central
• CRISPR-Cas9 genetic screen leads to the discovery of L-Moses, a KAT2B inhibitor that attenuates Tunicamycin-mediated neuronal cell death#211651Ora Oxford University Research
• CRISPR/Cas9-mediated PHOX2B functional knock-out in IMR32 neuroblastoma cells impairs neuronal excitability through dysregulation of ion channels genes.#354729NCBI PubMed Central
• A novel micelleplex for tumour-targeted delivery of CRISPR-Cas9 against KRAS-mutated lung cancer#365099Open Access LMU
• Customizable host and viral transcript enrichment using CRISPR-Cas9 long-read sequencing for characterization of low-to-moderate abundance isoforms.#975735NCBI PubMed Central
• Generation and characterization of a human iPSC cell line expressing inducible Cas9 in the "safe harbor" AAVS1 locus#646713Repisalud
• Genetic disruption of Pdcd-1 upstream enhancer boosts T cell function and antitumor responses#189772Kyoto University Research Information Repository
• Genetic disruption of Pdcd-1 upstream enhancer boosts T cell function and antitumor responses#189811Kyoto University Research Information Repository
• A molecular rheostat of ABA signaling coordinates the trade-off between stem growth and drought adaptation#379966Figshare
• Molecular characterisation of industrially relevant clostridium botulinum strains#447197University of Nottingham Repository
• Recent Advances in Pathogenicity and Biocontrol of Postharvest <i>Penicillium</i> Diseases#5871Europe PMC
• Integration of molecular and remote sensing techniques to enhance drought tolerance in soybean#332262ARPHA OAI-PMH Endpoint
• Impact of chromatin context on Cas9-induced DNA double-strand break repair pathway balance#644208IRIS
• Enhanced proofreading governs CRISPR–Cas9 targeting accuracy#614687eScholarship
• CRISPR/Cas9-modified Human T Cell ( PD-1and ACE2 Knockout Engineered T Cells ) for Inducing Long-term Immunity in COVID-19 Patients#127613ClinicalTrials.gov
• A new cerkl mouse model generated by CRISPR-Cas9 shows progressive retinal degeneration and altered morphological and electrophysiological phenotype#246159Dipòsit Digital de la Universitat de Barcelona
• Delayed nuclear localization of CRISPR/Cas9-modified fiber of Fowl Adenovirus serotype 8b reduces pathogenicity in specific pathogen-free chicken embryonic liver cells#310100Universiti Putra Malaysia Institutional Repository
• Phytohormone-Mediated Regulation of Plant Cold Stress Tolerance: Signaling, Hormonal Crosstalk, and Translational Perspectives#253701Europe PMC
• CRISPR-CAS9 Modified CD34+ Human Hematopoietic Stem and Progenitor Cells and … — Vertex Pharmaceuticals Incorporated (US20250041349A1)#653949Google Patents
• A Safety and Efficacy Study Evaluating CTX001 in Participants With Transfusion-Dependent β-Thalassemia#892461ClinicalTrials.gov
• Epitranscriptomic Remodeling of N6-Methyladenosine (m6A) RNA Marks in CRISPR-Edited Genomes: Emerging Implications for Off-Target Genetic Instability and Precision Gene Therapy#303039Zenodo (CERN)
• Generation of Leucine-rich repeat kinase 2 (LRRK2) knockout neuroblastoma cells SH-SY5Y by CRISPR/Cas9-mediated genome editing#413456Universiti Putra Malaysia Institutional Repository
• Compositions and methods of engineered CRISPR-Cas9 systems using split-nexus … — Caribou Biosciences, Inc. (US11111506B2)#607483Google Patents
• Extrahepatic Gene Editing In Vivo Using Organic Solvent‐Free Lipid Nanoparticles#213176HAL (France)
• Insights into the genetic architecture of resistance to viral haemorrhagic septicaemia virus in rainbow trout from a genome-wide association study to in vitro CRISPR-Cas9 functional evaluation#356373bioRxiv / medRxiv
• Genetic markers of polycystic ovarian syndrome: A descriptive review#383727Digital Commons @ Michigan Tech
• Comparative analysis of CRISPR/Cas9 delivery approaches for polyphenol oxidase 2 gene editing in potato#436064DSpace
• Optimized crispr/cas9 systems and methods for gene editing in stem cells — Editas Medicine, Inc. (US20230126434A1)#607213Google Patents
• Sequential CD146 and GPC3 CAR-T Cell Therapy in Advanced Ovarian Cancer#915109ClinicalTrials.gov
• Crispr/cas9-based compositions and methods for treating retinal degenerations — The Johns Hopkins University (US20240336934A1)#607477Google Patents
• Supplementary datasets for " Harnessing endogenous CRISPR-Cas9 for inducible genetic engineering of Apilactobacillus kunkeei "#303069api.researchdata.se
• Generation and immunofluorescent validation of gene knockouts in adult human colonic organoids using multi-guide RNA CRISPR-Cas9#1001269ScholarBank@NUS
• Unveiling the potential of banana (<i>Musa</i> spp.) improvement through genetic manipulation: current trends and future implications#120201Europe PMC
• Transcriptomic data and editing rate quantification of apple knock-out transgenic lines for a family of 17 amaranthin-like lectins#178209HAL (France)
• CRISPR/Cas9-Mediated Editing in FAD2 Gene to Enhance Oil Quality in Soybean [Glycine max (L.) Merrill]#1053091Europe PMC
• Inhibitors of crispr-cas9 — The Regents Of The University Of California (US20230287058A1)#607478Google Patents
• Developing a Human Cerebral Organoid Epilepsy Model for Studying Live 4D Mitochondrial Dynamics in Response to Ketogenic Diet Treatment#983536eScholarship
• Gene Editing and Assisted Reproduction: A Theological Exploration of the Moral Boundaries of Human Intervention in the African Context#368883OSF
• Comparative potato genome editing: Agrobacterium tumefaciens-mediated transformation and protoplasts transfection delivery of CRISPR/Cas9 components directed to StPPO2 gene#436062DSpace
• Using CRISPR Cas9 to successfully knock out the Or15 odorant receptors in Aedes aegypti mosquitoes & Fitness Assessment and SEPARATOR efficiency for Next Generation Sterile Insect Technique Lines#996321eScholarship
• A Whole Genomic CRISPR/Cas9 Screen Identifies the Amino Acid Transporter SLC43A1 (LAT3) as a Major Determinant of Oxaliplatin Sensitivity in Colorectal Cancer Cells#485210Europe PMC
• … and methods for improving homogeneity of dna generated using a crispr/cas9 … — Christiana Care Gene Editing Institute, LLC (US20230091847A1)#607476Google Patents