mendelian-randomization

Documents about mendelian-randomization

• Causal relationships between insomnia and blood metabolome: a Mendelian randomization study with mouse experimental validation.#227660NCBI PubMed Central
• The causal association between sleep traits and osteoarthritis traits: evidence from bidirectional mendelian randomization.#251128NCBI PubMed Central
• Inflammation and postoperative complications after major surgery: a bi-directional two-sample Mendelian randomization study#259235bioRxiv / medRxiv
• Causal effect of thyroid function on cortical brain structure: A two-sample Mendelian randomization study.#315756NCBI PubMed Central
• Causal relationships between irritable bowel syndrome and brain functional networks: A Mendelian randomization study.#334738NCBI PubMed Central
• Relationship between mental disorders and non-traumatic cerebral hemorrhage: cross-sectional analysis and mendelian randomization.#338318NCBI PubMed Central
• Checking Genetic Homogeneity Between Two Samples Using Summary Statistics With Application to Mendelian Randomization.#354871NCBI PubMed Central
• MRI-Derived Fat Depots and Cardiometabolic Pathways Underlying Heart Failure Risk: A Mendelian Randomization Study#438538bioRxiv / medRxiv
• Mendelian Randomization Research Examining the Effects of Insomnia on Herpes Zoster and Postherpetic Neuralgia.#610505NCBI PubMed Central
• Disentangling the association between chronic pain and sarcopenia-related traits: A bidirectional Mendelian randomization study.#645196NCBI PubMed Central
• Application of Mendelian randomization to appraise causality in relationships between the gut microbiome and cancer#5030Europe PMC
• Testing bidirectional associations of major depressive disorder with medical conditions: two-sample Mendelian randomization study#5439Europe PMC
• Repurposing drugs for the prevention of vascular dementia using evidence from drug target Mendelian randomization.#125301NCBI PubMed Central
• Drug-Target Mendelian Randomization and Imaging Mediation Analyses Reveal Therapeutic Targets and Causal Mechanisms for Cardiomyopathies#214807bioRxiv / medRxiv
• Integrative Genetic Analyses of Lipid Metabolism and Multiple Sclerosis Severity Using Metabolome-Wide and Cis-Mendelian Randomization#318551bioRxiv / medRxiv
• Inflammation and postoperative complications after major surgery: a bi-directional two-sample Mendelian randomization study#387705Europe PMC
• Chronic low back pain causal risk factors identified by Mendelian randomization: a cross-sectional cohort analysis.#458579NCBI PubMed Central
• Evaluating the Impact of Putative Metformin Targets on Cancer Outcomes: A Drug-Target Mendelian Randomization Study.#9407NCBI PubMed Central
• Association of Obstructive Sleep Apnea With Risk of Myocardial Infarction: A Multivariable Mendelian Randomization and Mediation Analysis#143870bioRxiv / medRxiv
• Clinical implications of bone marrow adiposity identified by phenome-wide association and Mendelian randomization in the UK Biobank#178072HAL (France)
• Causal relationships between somatic movement, brain structures, and mental well-being: A multi-stage Mendelian randomization study.#185872NCBI PubMed Central
• Appraising the causal relationship between kidney function and hearing performance: a two-sample Mendelian randomization study.#193579NCBI PubMed Central
• Causal relationship between inflammatory proteins and attention deficit hyperactivity disorder: A serum-metabolites-mediated Mendelian randomization analysis.#250965NCBI PubMed Central
• Causal association analysis between 731 immune cells and cystitis: A 2-sample, bidirectional Mendelian randomization study.#251047NCBI PubMed Central
• The role of lipid-lowering drugs in urologic and male reproductive cancers: a Mendelian randomization study.#281009NCBI PubMed Central
• Exploring the cognitive effects of arthritis: A Mendelian randomization study and cross-sectional analysis of NHANES data.#388629NCBI PubMed Central
• Genetically inferred effects of brain structure and gene expression on neurodegenerative diseases: a Mendelian randomization study.#423051NCBI PubMed Central
• Interpretable machine learning and mendelian randomization identify risk factors for lower extremity arterial embolism and thrombosis.#439010NCBI PubMed Central
• The Causal Effects of Inflammation and Coagulation-Related Biomarkers on Sepsis-Related Complications: A Mendelian Randomization Study.#182419NCBI PubMed Central
• The causal interplay between depression and alcohol use from adolescence to young adulthood: a Mendelian randomization study.#186180NCBI PubMed Central
• The genetic architecture of multimodal human brain age#257816Infoscience
• Integrating Pharmacovigilance Data Mining and Mendelian Randomization to Identify Risk Profiles and Causal Targets of Opioid‐Induced Delirium.#288899NCBI PubMed Central
• Frailty index and type 2 diabetes with renal complications: insights from Mendelian randomization and retrospective observational study.#312467NCBI PubMed Central
• Integrating multi-omics and mendelian randomization identifies therapeutic targets for Lichen Sclerosus: A druggable genome-wide study.#360636NCBI PubMed Central
• An Exposure-Wide and Mendelian Randomization Approach to Identifying Modifiable Factors for the Prevention of Depression#384228CiNii
• Integrative analysis of FAERS, network toxicology, and Mendelian randomization identifies potential targets in paclitaxel-associated systemic sclerosis.#399731NCBI PubMed Central
• Genetic predisposition to loneliness increases schizophrenia and depression risk through inflammatory pathways: a Mendelian randomization study#430021Europe PMC
• Age at first sexual intercourse and frailty: Mendelian randomization and population-based evidence from NHANES and UK Biobank.#645494NCBI PubMed Central
• Simultaneously accounting for the winner's curse and sample structure in Mendelian randomization: bivariate rerandomized inverse variance weighted estimator#682603arXiv (OAI Expanded)
• Simultaneously accounting for the winner's curse and sample structure in Mendelian randomization: bivariate rerandomized inverse variance weighted estimator#684378arXiv (All)
• Neutrophil extracellular traps-associated candidate genes in IgA vasculitis: an exploratory multi-omics analysis integrating transcriptomics and Mendelian randomization.#13601NCBI PubMed Central
• Genetic liability to endometriosis and pregnancy outcomes: a two-sample Mendelian randomization study with maternal-fetal effect decomposition#152669bioRxiv / medRxiv
• Genetic mechanisms of primary biliary cholangitis and its association with immune cells using mendelian randomization and biological annotation.#251143NCBI PubMed Central
• A Comparative Analysis of the Lipoprotein(a) and Low-Density Lipoprotein Proteomic Profiles Combining Mass Spectrometry and Mendelian Randomization#268549HAL (France)
• Circulating Protein–Mediated Pathways in Basal Cell Carcinoma: Mendelian Randomization Reveals STAT3 and GUCA1A as Key Regulatory Hubs.#280936NCBI PubMed Central
• Deciphering cell type-specific causal genetic effects on brain imaging-derived phenotypes and disorders with single-cell Mendelian randomization.#308760NCBI PubMed Central
• Genetically predicted childhood traits and parental health and risk of pediatric psychiatric disorders: A 2-sample Mendelian randomization study.#322833NCBI PubMed Central
• Low-Density Lipoprotein Cholesterol and Dementia Risk: Integrating Mendelian Randomization and Target Trial Emulation Within the Heart-Brain Axis#373574bioRxiv / medRxiv
• Shared genetics between ADHD and reading/language abilities: Genome-wide correlations, stratified enrichment, cross-trait association, and mendelian randomization.#382325NCBI PubMed Central
• Can we identify people with Alzheimer’s disease from examination of the eye? A bidirectional Mendelian randomization (MR) study.#382402NCBI PubMed Central