systems-biology

Documents about systems-biology

• Animal models in molecular biology research: Challenges, ethical imperatives, and the path to human-relevant translation.#388784NCBI PubMed Central
• The Boolean Breast-Cancer Network (BBCN): structural controllability of cell-fate signalling and a bistable resistance-apoptosis switch#435617bioRxiv / medRxiv
• Insulin resistance, aging biology, and non- communicable chronic diseases: a narrative review of bidirectional mechanisms and translational implications.#446108NCBI PubMed Central
• Global analysis of the cold-shock response in the model antibiotic producing actinomycete, Streptomyces coelicolor A3(2)#619167bioRxiv / medRxiv
• Effects of neutral selection on the evolution of molecular species#639098arXiv (OAI Expanded)
• Large-scale evolution and extinction in a hierarchically structured environment#639104arXiv (OAI Expanded)
• Extinction, diversity and survivorship of taxa in the fossil record#639122arXiv (OAI Expanded)
• The Evolutionary Biology of Ourselves: Unit Requirements and Organizational Change in United States History#639126arXiv (OAI Expanded)
• A Mathematical Model with Modified Logistic Approach for Singly-Peaked Population Processes#639127arXiv (OAI Expanded)
• Mathematical description of the heat transfer in living tissue (Part I)#639152arXiv (OAI Expanded)
• Mathematical description of the heat transfer in living tissue (Part II)#639153arXiv (OAI Expanded)
• Dynamic knowledge representation of blood brain barrier activation, injury and restitution with a novel agent-based model#663837bioRxiv / medRxiv
• Atomistic Simulations of Fe(CO)₅ Fragmentation Dynamics on a Substrate#253460Figshare
• Flow-Through Multiplex Bioassays Using Micropore-Confined Bipolar Electrochemiluminescence and Structural Color-Coded Conductive Microbeads#609513Figshare
• Search and clustering orders of magnitude faster than BLAST#6361OpenAlex
• Systems Biology on Gene Expression Dynamics Conserved from E. coli to Human(<Special Issue>Emergent Intelligence on Networks)#69776J-STAGE (Japan)
• Cost-saving, trading, and internalization of externality: three economic strategies underlying amino acid archetypes of human metabolic enzymes#141217bioRxiv / medRxiv
• Antibody-drug conjugates for infectious and neglected tropical diseases: chemical design principles, target biology, and translational challenges.#152247NCBI PubMed Central
• A biology-based quality-diversity algorithm for drug repurposing in Alzheimer's disease using automated machine learning.#174566NCBI PubMed Central
• EMERALD-UI: an interactive web application to unveil novel protein biology hidden in the alternative alignment space.#224798NCBI PubMed Central
• Network Analysis and Maximum Entropy Approaches in Complex Agroforestry Systems#236841OSF
• Algorithmic Political Bias in Artificial Intelligence Systems#292722OpenAlex
• Full-Body AI Agent: A Perspective on Multi-Scale Collaborative AI for Systemic Biology and Precision Medicine.#326974NCBI PubMed Central
• Traits and hidden states: is self-fertilization associated with rates of diversification across mating and sexual systems?#381639bioRxiv / medRxiv
• MYCN-driven metabolic remodelling of the tumour microenvironment in neuroblastoma: implications for stromal biology and CAF heterogeneity.#404375NCBI PubMed Central
• Revolutionizing the understanding of acupoint biology and acupuncture mechanisms through spatial omics: current perspectives and future directions.#430755NCBI PubMed Central
• Distinctive spore architecture and developmental biology of Turicibacter sanguinis reveal unexpected diversity among gut spore formers.#472606NCBI PubMed Central
• Numerical and comparative analyses of the modern systems of classification of the flowering plants#484885BioMed Central
• Host cell entry receptors as pharmacological targets in respiratory viral infections: from biology to clinical translation.#636456NCBI PubMed Central
• Decline in extinction rates and scale invariance in the fossil record#639118arXiv (OAI Expanded)
• Quantum effects in biology: master equation studies of exciton motion in photosynthetic systems#971602arXiv (All)
• Breaking the Stability-Activity-Selectivity Trilemma in Unspecific Peroxygenase through Computation-Based Cross-Regional Combinatorial Mutagenesis#329778Figshare
• Marginal Girsanov Reweighting: Stable Variance Reduction for Long-Time-Scale Dynamics from Biased Simulation#661896Figshare
• Dynamics of Complex Systems: Biological and Environmental Coevolution Preceding the Cambrian Explosion#3407MIT OpenCourseWare
• Cell-Type-Resolved Pseudobulk Classification Across Independent Cohorts Identifies Microglial PTPRG as a Transcriptional Hub in Alzheimer's Disease#165964bioRxiv / medRxiv
• Phase 3 Transition Note, Lantern of Sulfur, Convergence, v12, May 2026#212724Zenodo (CERN)
• Recent advances in bioengineering and functional applications of microbial biocomposites: integrating bacterial cellulose, fungal mycelium and synthetic biology.#214081NCBI PubMed Central
• The evolving role of structural biology in pharma: integration of X-ray crystallography, cryo-electron microscopy and beyond.#251072NCBI PubMed Central
• Interspecific divergence of gene expression biophysics driven by both evolutionary systems drift and strong selective constraints on bursting rate#353146bioRxiv / medRxiv
• Diversity and Spatial Segregation of TRP Channels in Choanoflagellates Provide Insight into the Evolutionary Origin of Animal Sensory Systems#366447bioRxiv / medRxiv
• Informed Data-Independent Acquisition Enables Targeted Quantification of Key Regulatory Proteins in Cell Fate Decisions at Single-Cell Resolution#448034bioRxiv / medRxiv
• The effects of natural and anthropogenic factors on microbes decomposing the emerging macrophyte Scirpus lacustris in prairie aquatic systems.#485098Europe PMC
• Asymmetric co-substrate usage at a metabolic branch point as a minimal network motif that can drive overflow metabolism#640102bioRxiv / medRxiv
• Determinacy as Relational Achievement: _Symmetry, Constraint, and Individuation_ in Physics (Quantum Mechanics), Biology (Biosemiotics), and Interactive Formal Systems (Large Language Models)#714910PhilArchive
• Emerging synthetic biology-assisted technologies for overcoming antibiotic resistance: CRISPR-Cas, bacteriophage, microbiome, and metabolic engineering-based solutions.#988593NCBI PubMed Central
• A survey of floral traits, breeding systems, floral visitors, and pollination systems of the angiosperms of the Juan Fernández Islands (Chile)#484840BioMed Central
• The Single Pole Battery: a Relativistic Understanding and Generalization of Clausius' Concept of Entropy#15971OSF
• Oral LNAD+ Rapidly Elevates Intracellular NAD and Metabolic Flux Without Elevating Circulating NAD: Evidence from a Randomized Controlled Trial#226033bioRxiv / medRxiv
• Study on Liver Sinusoidal Endothelial Cell Fenestrations Based on Cellular Omics-Structure Integration Technology and Its Application in Metabolic Diseases#314141bioRxiv / medRxiv
• Cyber-physical systems and internet of things#335801OpenAlex