Multi-Dot/Icm effector mutants reveal distinct host responses in <i>Legionella</i> infected macrophages

Legionella pneumophila is the causative agent of Legionnaires’ disease, an accidental and severe form of pneumonia. The replication of L. pneumophila within alveolar macrophages requires the Dot/Icm type IV secretion system that translocates more than 330 bacterial effector proteins into the infect