mitochondrial-dysfunction

Documents about mitochondrial-dysfunction

• Imbalance of mitochondria and abnormalities in lipid metabolism in Diabetic Tubulopathy#4728Europe PMC
• It's Not Rewarding for Mitochondria: Dopamine-Induced Mitochondrial Dysfunction Activates cGAS-STING to Drive IL-6 Secretion in Macrophages#222315bioRxiv / medRxiv
• Study On the Role of Mitochondrial Dysfunction in the Pathogenesis of Metformin-associated Lactic Acidosis#283226ClinicalTrials.gov
• The Role of lncRNA GAS5 in Oxidative Stress and Mitochondrial Dysfunction in Age-Related Cataracts: Insights From Transcriptome Profiling.#265387NCBI PubMed Central
• Enigma of autism regression mechanistic pathways, clinical phenotypes, and early intervention implications#273362Europe PMC
• The role of energy deficit in autophagy failure in Parkinson's disease#408588IBISS
• HYPERTENSION INDUCES ENERGETIC DERANGEMENTS AND EXAGGERATES HYPERTROPHIC REMODELING IN FABRY HEART#677806IRIS
• Para-dichlorobenzene inhibits Fusarium oxysporum f. sp. cubense tropical race 4 by inducing membrane damage, mitochondrial dysfunction, and transcriptional reprogramming.#157200NCBI PubMed Central
• Control of Renal Oxygen Consumption, Mitochondrial Dysfunction, and Insulin Resistance#463672ClinicalTrials.gov
• Novel <i>in vivo</i> measurement of muscle total carnitine concentration reveals potential mechanism linking mitochondrial dysfunction and lipid accumulation#475756Europe PMC
• Cell-free Mitochondrial DNA (mtDNA) Triggers Vascular Dysfunction via Toll-like Receptor 9 (TLR9)-dependent Activation of Inflammasomes#680651Scholar Commons
• Multi-omics liquid biopsy identifies mitochondrial dysfunction in geographic atrophy and supports the longevity-associated metabolite alpha-ketoglutarate as a therapeutic strategy#28597bioRxiv / medRxiv
• A Pilot Serum Metabolomics Reveals Mitochondrial Dysfunction and Identifies Methylguanidine as a Potential Diagnostic Biomarker for ATAAD with Mesenteric Malperfusion Syndrome.#140616NCBI PubMed Central
• miR-124 coordinates metabolic regulators acting at early stages of human neurogenesis#389963S-Space: Seoul National University
• Clinical Trial of High Dose CoQ10 in ALS#813065ClinicalTrials.gov
• Mitochondrial dysfunction and the regulatory cell death crosstalk network in chronic obstructive pulmonary disease: from oxidative stress mechanisms to targeted therapeutic strategies.#402563NCBI PubMed Central
• Acetyl-CoA synthetase 2 maintains cytosolic acetyl-CoA homeostasis to preserve mitochondrial integrity and attenuate cardiac dysfunction under chronic β-adrenergic stress.#662777NCBI PubMed Central
• Chronic Kidney Disease and Heart Failure With Preserved Ejection Fraction: The Role of Mitochondrial Dysfunction#808056ClinicalTrials.gov
• CSF IL-6, GDF-15, GFAP and NfL levels in early Alzheimer disease: a pilot study#202760IRIS
• Calcium overload-induced apoptosis in cancer cells: ER-mitochondria crosstalk and therapeutic implications#478481Europe PMC
• Liuwei Dihuang pills attenuates cognitive dysfunction in APP/PS1 mice through restoring mitochondrial homeostasis and activating the IRS/AKT/GSK3β insulin signaling pathway.#653473NCBI PubMed Central
• DHDDS-related juvenile parkinsonism is caused by impaired lipid metabolism, glycosylation, and mitochondrial dysfunction, which can be rescued by NAD⁺ treatment.#339588bioRxiv / medRxiv
• Mitochondrial dysfunction in the pathogenesis of Ullrich congenital muscular dystrophy and prospective therapy with cyclosporins#340182IRIS
• A novel spontaneous rat model of chronic kidney disease with mitochondrial dysfunction driven by thioredoxin insufficiency#355150OKAYAMA UNIVERSITY SCIENTIFIC ACHIEVEMENT REPOSITORY
• Role of Mitochondrial Dysfunction in the Occurrence of Acute Kidney Injury (AKI) in Postoperative Cardiac Surgery#448214ClinicalTrials.gov
• eMESH Struct. 2022-23#894624ClinicalTrials.gov
• MOLECULAR-BIOCHEMICAL MECHANISMS OF METABOLIC CHANGES IN THYROID DISEASES#161128Zenodo (CERN)
• Rivaroxaban suppresses factor Xa-Driven PAR-2-ERK inflammatory, catabolic, osteoclastogenic, and mitochondrial dysfunction signaling in osteoarthritis-relevant chondrocytes: a drug-repurposing strategy for joint inflammation.#923516NCBI PubMed Central
• Inducible nitric oxide synthase-derived nitric oxide promotes mitochondrial dysfunction, altered nutrient metabolism, and apoptosis in Ctns null kidney proximal tubular epithelial cells#471132Animo Repository
• Efficacy and Safety of Different Dosages of Mexidol® in Patients With Primary Open-angle Glaucoma (POAG)#846133ClinicalTrials.gov
• Plasma Level of ATPase Inhibitory Factor 1 and Intrinsic Capacity in Community-Dwelling Older Adults: Prospective Data From the MAPT Study#156203HAL (France)
• A distinct tau oligomer strain defines the molecular and proteomic landscape of rapidly progressive Alzheimer’s disease#398839HAL (France)
• Mitochondrial dysfunction plus high-sugar diet provokes a metabolic crisis that inhibits growth#934562Koc University Digital Collections
• Additional file 1 of In vitro toxicity of piperazine derivatives involves mitochondrial dysfunction and microtubule-related changes in neuronal cell models#377661Figshare
• Intranasal delivery of dodecyl creatine ester alleviates motor deficits and increases dopamine levels in a 6-OHDA rat model of parkinsonism#417983HAL (France)
• Understanding Alpha-Synuclein Spread in Parkinson's Disease Through Blood Biomarkers and Neuroimaging#966505ClinicalTrials.gov
• Evaluating the potential of hydrogen sulfide to improve health with age and spaceflight#470593University of Nottingham Repository
• Validation of the Snouda Metabolic Score for Phenotyping and Guiding Reversal in Type 2 Diabetes#844108ClinicalTrials.gov
• A double-blind, randomized placebo-controlled trial examining the effect of MitoQ on myocardial energetics in patients with dilated cardiomyopathy#256120Spiral
• Mechanisms of Synergy Between Nanosecond Pulsed Electric Field (nsPEF) and Cold Atmospheric Pressure Plasma Discharge (CAP) in Pancreatic Cancer: The Role of ROS-Mediated Oxidative Stress and Apoptosis#434501ODU Digital Commons
• Targeting of reactive isolevuglandins in mitochondrial dysfunction and inflammation#620084eScholarship