ubiquitination

Documents about ubiquitination

• A fish-specific E3 ubiquitin ligase NHRE3 suppresses antiviral immunity by degrading ISG15 via ubiquitination#1135369PLOS
• SUMOylation and ubiquitination reciprocally regulate SMCHD1 antiviral activity against herpes simplex virus 1#309474PLOS
• New mechanistic insight into SARM1 activation: TRIM32-mediated ubiquitination is a key lever that actuates SARM1’s catalytic action, leading to axon degeneration and cell death#653902OKAYAMA UNIVERSITY SCIENTIFIC ACHIEVEMENT REPOSITORY
• FibrilPaints for visualisation and ubiquitination of Huntingtin amyloid fibrils#261813Europe PMC
• BARD1 reads H2A Lys-15 ubiquitination to direct homologous recombination#654246PubMed Central
• Ubiquitin beyond proteins: NoPro-clipping reveals glycogen and metabolite ubiquitination.#430855NCBI PubMed Central
• Integrative multi-omics analysis identifies key ubiquitination regulators in prostate cancer.#157928NCBI PubMed Central
• Bisphenol-A mediated ubiquitinome alteration triggers PPAR-alpha ubiquitination, affecting trophoblast cell migration#264581bioRxiv / medRxiv
• Phase separation of MARCH1 promotes rectal adenocarcinoma progression through PHLPP2 ubiquitination.#368058NCBI PubMed Central
• Ubiquitination-mediated regulation of receptor-like kinases in symbiosis and immunity#395439HAL (France)
• Comparative ubiquitinomics of human skin reveals insulin receptor ubiquitination as a regulator of collagen secretion#1235375HAL (France)
• E3 ubiquitin ligase SYVN1 mediates K63-linked ubiquitination of DDX3X to activate Macrophage NLRP3 Inflammasome#1381487bioRxiv / medRxiv
• Decoding the ubiquitination-immunity axis in idiopathic pulmonary fibrosis: diagnostic insights and therapeutic implications.#25727NCBI PubMed Central
• Regulation of HPV-16 infection by ubiquitination of the L1 major capsid protein.#209550NCBI PubMed Central
• BTBD9-driven IMPDH2 ubiquitination governs sleep homeostasis by gating adenosine metabolism in the basal forebrain.#1480290NCBI PubMed Central
• Proteomic Profiling Reveals HECTD4-dependent Regulation of Protein Ubiquitination and Signaling Pathways in Prostate Cancer.#150053NCBI PubMed Central
• TRIM21 promotes astrocyte-mediated neuroinflammation in experimental autoimmune encephalomyelitis by stabilizing RGMa via K33-linked ubiquitination.#143307NCBI PubMed Central
• LUBAC PUB domain interactions restrict Met1-linked ubiquitination to prevent embryonic lethality and immune pathology#150363Europe PMC
• ERG activity is regulated by endothelial FAK coupling with TRIM25/USP9x in vascular patterning#291411Gestión del Repositorio Documental de la Universidad de Salamanca
• The Molecular Mechanism of RIG-I Regulation by LGP2#413187RUcore, Rutgers University Community Repository
• Ubiquitination-driven fibroblast dysfunction: a multi-omics blueprint for precision diagnosis and therapy in diabetic foot ulcer.#170576NCBI PubMed Central
• The TRAF6-Akt axis is required for efficient lytic replication of KSHV#631431PLOS
• LUBAC PUB domain interactions restrict Met1-linked ubiquitination to prevent embryonic lethality and immune pathology#152113Unpaywall
• LKB1 dictates sensitivity to immunotherapy through Skp2-mediated ubiquitination of immune checkpoint proteins in HCC with python analysis.#465063NCBI PubMed Central
• TRIM59 alleviates neuronal ferroptosis and promotes functional recovery after spinal cord injury by mediating ubiquitination and degradation of ANXA2.#4399NCBI PubMed Central
• TANK potentiates antiviral innate immunity by recruiting deubiquitinase USP46 to activate IKKε#362522PLOS
• COMPASS: A Computational Pipeline to Identify Linkers Predicting Ubiquitinable PROTAC‐Induced Ternary Complexes#670047HAL (France)
• <b>MLF2 Stabilizes KLF5 by Limiting FBXW7-Mediated Ubiquitination to Sustain PI3K/AKT Signaling in Gastric Cancer</b>#1097492Figshare
• Constitutive Endocytosis and Turnover of the Neuronal Glycine Transporter GlyT2 Is Dependent on Ubiquitination of a C-Terminal Lysine Cluster#1157931HAL (France)
• A feed-forward UHRF1 read-write mechanism supports H3 multi- mono-ubiquitination and DNA methylation maintenance at CpG-sparse regions#1442477bioRxiv / medRxiv
• Integrative Transcriptomics Identifies Ubiquitination-Related Genes BIRC2, COPS5, and TBK1 as Novel Biomarkers of T-Cell Dysregulation in Amyotrophic Lateral Sclerosis.#172021NCBI PubMed Central
• Lipid droplet on the move: remodeling, trafficking and interaction with other organelles#11650HAL (France)
• Ovarian tumor domain-containing protein 1 deficiency attenuates metabolic dysfunction-associated steatotic liver disease by promoting the ubiquitination of HSP90α in hepatocytes.#1054320NCBI PubMed Central
• Ubiquitin-proteasome system regulates pro-crossover protein dynamics during meiosis in <i>Caenorhabditis elegans</i>#285422PLOS
• CDCA8 regulates ATP5F1A protein stability and malignant phenotypes in wilms tumor cells: Prognostic implications and mechanistic insights#389538PLOS
• Hypercapnia impairs cell junction formation by promoting TRAF2 E3 ligase-mediated ubiquitination and endocytosis of the Na,K-ATPase beta-subunit in alveolar epithelial cells#644438JLUpub
• SARS-CoV-2 Nsp1 suppresses the canonical NF-κB pathway by promoting ubiquitin-dependent degradation of TAK1 kinase#152672PLOS
• Lysine deficiency within a conserved lysine desert is critical for EEL-1/HUWE1 to support ubiquitin proteasome system function#443292PLOS
• Heterozygous loss-of-function alleles associate the conserved 3&#039;-5&#039; exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5-fluorouracil#257564HAL (France)
• Bioinformatics analysis and single-cell RNA sequencing: elucidating the ubiquitination pathways and key enzymes in lung adenocarcinoma#935980Repositorio de Universidad Autónoma de Chile.
• Dog-human gene network colocalization links synaptic signalling and ubiquitination to compulsive disorders#808179api.researchdata.se
• The RING-Finger Ubiquitin E3 Ligase RFEL1 Targets Wheat NPR3 for Degradation to Confer Broad-Spectrum Resistance Against Biotrophic Fungal Pathogens#372535Scholar Commons
• Mezigdomide Plus Ixazomib and Dexamethasone for Relapsed and Refractory Multiple Myeloma#1057923ClinicalTrials.gov
• The ubiquitin-modifying enzyme A20 restricts ubiquitination of the kinase RIPK3 and protects cells from necroptosis#1250203eScholarship
• Tonic ubiquitination of the central body weight regulator melanocortin receptor 4 (MC4R) promotes its constitutive exit from cilia#1424806eScholarship
• Oligomerization of the Nrdp1 E3 Ubiquitin Ligase Is Necessary for Efficient Autoubiquitination but Not ErbB3 Ubiquitination*#1174918eScholarship