gene-editing

Documents about gene-editing

• A novel Leishmania infantum reference strain for gene editing and the study of visceral leishmaniasis#250415HAL (France)
• Development of new biotechnological tools to accelerate breeding in chestnut and hazelnut#422654IRIS
• Sequential gene editing in primary immune cells — Cellectis (US11674155B2)#607209Google Patents
• Novel Method of Circular RNA-based Blood Cell Reprogramming and Successful Downstream Gene Editing in Stable Human iPSC Lines#643615Harvard DASH
• Extrahepatic Gene Editing In Vivo Using Organic Solvent‐Free Lipid Nanoparticles#213176HAL (France)
• Environmental Risk Assessment and Confinement of Genetically Engineered Trees with an Emphasis on Vegetative Reproduction#676120Europe PMC
• UNCOVERseq enables sensitive and controlled gene editing off-target nomination across CRISPR-Cas modalities and systems#675832eScholarship
• Virus-Like Particles: The Next Frontier in Livestock Gene Editing#149881Unpaywall
• ALPINE: a scalable pipeline for comprehensive classification of gene-editing outcomes from long-read amplicon sequencing.#396081NCBI PubMed Central
• Knock-out of SlDMR6-1 in tomato promotes a drought-avoidance strategy and increases tolerance to Late Blight#468474IRIS
• Decoding the role of chromatin context in the off-target effects of CRISPR gene editing with EGOLD.#185891NCBI PubMed Central
• A genetic manipulation tool based on the GP35 recombinase for targeted gene editing in mycoplasmas of ruminants.#251166NCBI PubMed Central
• Base-Edited Hematopoietic Stem/Progenitor Cell X-Linked Severe Combined Immunodeficiency Gene Therapy#866774ClinicalTrials.gov
• A heterologous marker-free selection approach for CRISPR/Cas9-based gene editing in the malaria parasite Plasmodium falciparum.#143298NCBI PubMed Central
• Delivering the future of immunotherapy: A state-of-the-art review of gene editing in immune cells with lipid nanoparticles#291898HAL (France)
• In-Depth Characterization of Stem Cell Potency and Genotoxicity for Clinical-Scale Ex Vivo CRISPR/Cas9 Gene Editing#294242Europe PMC
• RNA-guided gene editing system and uses thereof — Novartis Ag (US10738290B2)#607214Google Patents
• Genetic transformation and CRISPR/Cas12a-mediated gene editing of European beech (Fagus sylvatica L.) employing a transient protoplast system#676156Europe PMC
• Navigating the human gene editing scene and proposing a new governance framework in Africa: from knowledge to policy to action.#449674NCBI PubMed Central
• A critical review of the ethical and legal issues in human germline gene editing: Considering human rights and a call for an African perspective#767678PhilArchive
• Mapping the Fate of Retinal Progenitors Using Gene-Editing Technologies in Retinal Organoids#983529eScholarship
• From designer babies to edited food: comparing public attitudes toward CRISPR technology and gene editing in Japan and the United States.#219156NCBI PubMed Central
• AI-enhanced framework for optimizing CRISPR-Cas gene editing in crop biotechnology addressing regulatory challenges and opportunities in global agricultural practices.#418310NCBI PubMed Central
• Compositions and methods for enhancing triplex and nuclease-based gene editing — Yale University (US20260048118A1)#607210Google Patents
• Exploiting Epigenome Editing in Kabuki Syndrome: a New Route Towards Gene Therapy for Rare Genetic Disorders#870969ClinicalTrials.gov
• Methods for improved plant gene-editing — Inari Agriculture Technology, Inc. (US12043838B2)#607208Google Patents
• Vector-free delivery of gene editing proteins and compositions to cells and … — Avectas Limited (US20240279683A1)#607212Google Patents
• Compositions for enhancing targeted gene editing and methods of use thereof — Yale University (US11136597B2)#607216Google Patents
• Genome engineering in mammalian cells by Flp and Cre DNA recombinase variants#957658Louisiana Tech Digital Commons
• Advancing climate adaptation in saffron through CRISPR-based modulation of stress tolerance and photoperiodic flowering control.#9761PubMed
• The ethylene‐responsive transcription factor ERF024 is a novel regulator of climacteric fruit ripening in melon#173057HAL (France)
• Gene editing systems comprising a crispr nuclease and uses thereof — Arbor Biotechnologies, Inc. (US20240102007A1)#607217Google Patents
• Choice of template delivery mitigates the genotoxic risk and adverse impact of editing in human hematopoietic stem cells#176851HAL (France)
• Desenvolvimento de linhagens de Saccharomyces cerevisiae com fenótipo POF (Phenolic Off-Flavor) negativo por edição do gene FDC1 via sistema CRISPR/Cas9#977204RI UFSCar
• Closed process for expansion and gene editing of tumor infiltrating lymphocytes … — Ióvance Biotherapeutics, Inc. (US12495791B2)#607207Google Patents
• Boosting Ligand-Mediated Hepatic mRNA Delivery and Gene Editing Through Coordinated Pairing of Polyethylene Glycol-Modified Lipids#664982Figshare
• Epitranscriptomic Remodeling of N6-Methyladenosine (m6A) RNA Marks in CRISPR-Edited Genomes: Emerging Implications for Off-Target Genetic Instability and Precision Gene Therapy#303039Zenodo (CERN)
• Optimized crispr/cas9 systems and methods for gene editing in stem cells — Editas Medicine, Inc. (US20230126434A1)#607213Google Patents
• Effect of childhood general traumas on suicide attempt depends on TPH2 and ADARB1 variants in psychiatric patients#643944IBISS
• Peptide-mediated delivery of CRISPR enzymes for the efficient editing of primary human lymphocytes#676008eScholarship
• Investigating the potential role of mechanistic target of rapamycin complex 1 (mTORC1) in regulating cell fate decisions in Dictyostelium discoideum#225003Ora Oxford University Research
• Evolved cas9 proteins for gene editing — President And Fellows Of Harvard College (US20250092374A1)#607206Google Patents
• How to ‘future proof’ benefit-sharing from the use of DSI in agricultural research and development#809938CGSpace
• CGIAR capacity sharing with NARS to use digital sequence information in conservation and crop improvement programs. A submission from CGIAR for consideration by the Governing Body of the International Treaty#809932CGSpace
• Gene Editing and Assisted Reproduction: A Theological Exploration of the Moral Boundaries of Human Intervention in the African Context#368883OSF
• Therapeutic applications of CRISPR/Cas9 mediated targeted gene editing in acute lymphoblastic leukemia : current perspectives, future challenges, and clinical implications#187918Repositório Institucional da UnB
• Supplementary Information of "Robust genome editing in multiple dicot crops via a Cas9-TREX2 fusion with intron-mediated polycistronic tRNA-sgRNA system"#226645Figshare
• Generation and characterization of a human iPSC cell line expressing inducible Cas9 in the "safe harbor" AAVS1 locus#646713Repisalud
• A Study to Evaluate the Safety and Pharmacokinetics of RC001 in Children With Dravet Syndrome#845758ClinicalTrials.gov
• Enhancing endonuclease based gene editing in primary cells — Seattle Children's Hospital (dba Seattle Children's Research Institute) (US20200377911A1)#607215Google Patents